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Showing 1 to 2 of 2 for “"N-sulfinyl metallodienamine"”.
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NATURAL PRODUCT INSPIRED METHODOLOGIES: ADVANCES IN DIASTEREOSELECTIVE N-SULFINYL IMINE AND TRIFLUOROPYRUVIC ACID REACTIONS
… products. In the Andrade lab I developed N-sulfinyl metallodienamine (NSMD) and metalloenamine (NSME) methodologies for the asymmetric synthesis of natural products. In 2017, our first report of a novel diastereoselective hydroxylation protocol for metallodienamine (with 4:1 dr) in concise …
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DISCOVERY OF NOVEL MACROLIDE ANTIBIOTICS AND METHODOLOGY DEVELOPMENT OF N-SULFINYL METALLODIENAMINES
… antibiotics and methodology development of N-sulfinyl metallodienamines. To tackle bacterial resistance, new antibiotics are desperately needed. My research objective is to address this need by designing, synthesizing, and evaluating novel macrolide antibiotics based on the best-in-class drug …