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Showing 1 to 3 of 3 for “"N-acyl iminium"”.

  1. Asymmetric Synthesis of 1,3-Amino Alcohols and Tropinone Derivatives From Enantiopure Sulfinimines

    … N-sulfinyl ketones. After reaction with an acylating agent, the tropinone nucleus can be formed through an intramolecular Mannich reaction of an N-acyl iminium ion.

    temple Repository record for Asymmetric Synthesis of 1,3-Amino Alcohols and Tropinone Derivatives From Enantiopure Sulfinimines (opens in a new tab)

  2. Development and application of new strategies for synthesis of complex diketopiperazine alkaloids

    … chemistry is strategically critical to access N-acyl iminium ion intermediates necessary for nucleophilic thiolation of advanced diketopiperazines en route to potent epipolythiodiketopiperazine anticancer compounds. In this study, we develop an informative mathematical model using hydantoin …

    mit Repository record for Development and application of new strategies for synthesis of complex diketopiperazine alkaloids (opens in a new tab)

  3. Complex botanical natural products: Synthesis of cephalotaxus esters and of the C19-diterpenoid skeleton of aconitum and delphinium alkaloids

    … of P-388 murine leukemia cells. While direct acylation of cephalotaxine has been reported to be difficult, the construction and acylation of cephalotaxine using a β-lactone acyl chain surrogate in the synthesis of anhydroharringtonine, deoxyharringtonine, homodeoxyharringtonine, and …

    uiuc Repository record for Complex botanical natural products: Synthesis of cephalotaxus esters and of the C19-diterpenoid skeleton of aconitum and delphinium alkaloids (opens in a new tab)