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Showing 1 to 2 of 2 for “"N-Acetylglucosaminyltransferases"”.
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Impaired N-Glycosylation Processing Impacts Neuronal Function
… is performed by enzymes known as N-acetylglucosaminyltransferases (GnTs). Encoding of GnT proteins is performed by genes known as Mgats. Kv3.1b is an alpha subunit of a voltage-gated potassium channel known as Kv3 channels. Kv3 channels have the ability to open and close much more …
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Development of New Photocrosslinking Approaches to Discover Binding Partners of O-GlcNAc-Modified Proteins
O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant post-translational modification that is regulated by two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (OGA). While it is elusive how O-GlcNAc alters protein function, altered O-GlcNAc levels are associated with human diseases. …