Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Myristic Acid"”.
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Antimycobacterial activity of the red algae gelidium pristoides, plocamium corallorhiza and polysiphonia virgata
… the major bioactive compound. Long chain fatty acids were responsible for the antimycobacterial activity of the algal extract particularly oleic acid, linoleic acid, dodecanoic acid, and myristic acid. Oleic acid inhibited the growth of M. tuberculosis at and MIC-value of 25 11 g/rnL, while …
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Towards the development of a multicomponent, nanoscale oral vaccine delivery system targeting infectious bursal disease (IBD)
… meet this end. By encapsulation within a fatty acid coated, protein adsorbed-solid core drug delivery system (SCDDS), it was shown that a model protein antigen (GST-GFP) could be protected from low pH (i.e. pH 2.0) and proteases. Protease protection was demonstrated against the exposure of …
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Studies into solid core drug delivery system using haemoglobin as a model drug and supercritical fluid processing for encapsulation
… material for protein immobilisation and fatty acids coating was performed using supercritical carbon dioxide (CO2) as a processing media. The melting behaviour of saturated fatty acids (lauric, myristic, palmitic and stearic acid) and pluronics (F-38, F-68, F-77, F-127 and F-108) were studied …
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Analysis of Therapeutic Effect after Human Mesenchymal Stem Cell Transplantation in Ischemic Stroke Rat
… in ischemic rats, changes in free fatty acids (FFA) levels and proteins were detected in 4 days after MSC transplantation (Part 1, 2). I also evaluated the impact of the passage of MSCs on their effects in a rat stroke model (Part 3). Part I: Although ex vivo culture-expansion is …
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The investigation of the effect of free organic anions on scale inhibitors used to prevent nucleation occurring in oil rig wells, using dynamic test equipment.
… problems. The oil from this field is very acidic. It is believed that these anions associate themselves with the scale inhibitors and so reduce the efficiency of the scale inhibitor. The identity and amount of the acids affecting the scale inhibitor needs to be found. This was preformed …
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Assessment of <i>N</i>-myristoyltransferase and the <i>N</i>-myristoylomeas a potential chemotherapeutic target in<i>Trypanosoma cruzi</i>
… of the epimastigote wereidentified using the myristic acid analog, azidomyristate and a chemical proteomicsapproach. Combining label-free and SILAC methodologies, 38 proteins were enrichedfrom azidomyristate labelled cells, 35 of which were predicted to have a glycine afterthe initial …
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The preparation of solid core drug delivery system (SCDDS) via supercritical processing of fatty acids
… and were coated with different ratios of fatty acid. A proportional increase in particle size was observed with increasing ratio of fatty acid in the formulation. Coating of silica particles with smaller chain fatty acids (lauric and myristic acid) resulted in a higher increase in particle size …
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Polymorph Selection with Morphology Control Using Solvents and Additives
… well-defined morphology using additives. Adipic acid, myristic acid, oleic acid and structurally related 3-indoleacetic acid were selected as additives and their impact on the morphology and polymorphism of indomethacin were investigated in this study. Additives did not change the needle-like …
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Nanostrucured Lithium Iron Phosphate As Cathode Material For Lithium Ion-Batteries
… with different amount of surfactant, lauric acid that acts as carbon source. We were able to show that an optimized amount of carbon results in greatly improved room-temperature electrochemical performance. On the other hand, because the electrochemical properties are strongly dependent on …
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Apolipoprotein M – Studies of Structure and Function
… and its two metabolites, all-trans retinoic acid and 9-cis retinoic acid. After successful crystallization trials we managed to determine the 3D structure of recombinant apoM expressed in E.coli. ApoM displays the typical lipocalin fold that was predicted, i.e. characterized by an 8-stranded …
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Effects of dietary fat saturation on lipoprotein metabolism in rodents and humans
<p>Consumption of trans-fatty acids (tFA) and saturated fatty acids (SFA) have been associated with higher incidence of coronary heart disease. Experimental and observational data suggests that consumption of PHVO containing tFA, like SFA leads to increased total cholesterol and LDL-cholesterol …
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Destruction of algae-produced taste-and-odor compounds by chlorine, potassium permanganate, and chlorine dioxide
… by Rashash (1994) and are as follows: isovaleric acid (rancid, dirty socks), β-cyclocitral (tobacco, grape), phenethyl alcohol (roses), myristic acid (odorless), palmitic acid (odorless), linoleic acid (odorless), and linolenic acid (watermelon). All seven compounds were oxidized and evaluated by …
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Intracellular growth of Brucella abortus and B. melitensis in murine macrophage-like cell lines and partial characterization of a biologically active extract from B. abortus strain RB51
… by sensitized splenocytes. The N-terminal amino acid sequences of these two proteins were obtained and their putative DNA sequences deduced. Another antigen known to be a component of the S2 extract is the lipopolysaccharide (LPS). Polymyxin B is thought not to bind B. abortus LPS as it does not …
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Trimming Fat Upon Infection: Proteolytic Demyristoylation as a Novel Bacterial Pathogenic Strategy
Host-pathogen interaction is a complex process that involves an array of molecular tools on both sides of the conflict. In the light of growing antibiotics resistance, understanding of virulence factors utilized by pathogenic bacteria is crucial for developing better treatment for infectious …
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Characterizing the Binding Potential, Activity, and Bioaccessibility of Peroxisome Proliferator Activated Receptor Gamma (PPARγ) Ligands in Indoor Dust
… found to readily hydrolyze to tetrabromobenzoic acid (TBBA) in the intestinal fluid in the presence of lipases. </p><p> In research aims 2 and 3, two commercially available high-throughput bioassays, a fluorescence polarization PPAR ligand binding assay (PolarScreenTM PPARγ-competitor assay kit, …