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Showing 1 to 15 of 15 for “"Myricetin"”.
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Molecular mechanisms of myricetin bulk and nano forms mediating genoprotective and genotoxic effects in lymphocytes from pre-cancerous and myeloma patients
… dietary intake of various flavonoids such as myricetin have a protective effect against different types of cancers and cardiovascular diseases. The present study was conducted to investigate the genoprotective and genotoxic effects of myricetin nano and bulk forms on the lymphocytes from …
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Molecular mechanisms of myricetin bulk and nano forms mediating genoprotective and genotoxic effects in lymphocytes from pre-cancerous and myeloma patients
… dietary intake of various flavonoids such as myricetin have a protective effect against different types of cancers and cardiovascular diseases. The present study was conducted to investigate the genoprotective and genotoxic effects of myricetin nano and bulk forms on the lymphocytes from …
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Purification and characterization of A[beta] and probing the interactions between myricetin and A[beta] using various spectroscopic methods
… forms of interaction between A[beta] and myricetin, a flavonoid compound. In this study, two A[beta] fragments, A[beta](1-16) and A[beta](25-40), together with A[beta](1-42) were investigated. HPLC purification was conducted on crude A[beta](1-16) and A[beta](25-40) using a Beckman System …
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Using Esterase and Laccase Enzymes to Derivatize Bioactive Plant Phenolics for Altered Chemistry
… resveratrol, quercetin, morin, kaempferol and myricetin. Among the products formed by action on flavonols were dimers of quercetin, morin, and myricetin. Quercetin and myricetin dimers showed longer retention time on reversed phase chromatography. All three dimers could be detected by 5 min of …
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The cardioprotective mechanisms of dietary flavonoids
… of the dietary flavonoids quercetin, kaempferol, myricetin and two major quercetin metabolites, quercetin-3-glucoronide and 3’-O-methylquercetin, on fully differentiated H9c2 cells for the first time. The cardiomyocyte-like phenotype of the differentiated H9c2 cells was confirmed by monitoring the …
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Characterization, Interaction and Chemoprevention of Potent Constituents From Grape Cell Culture
… Epicatechin gallate (IC 50 = 0.029 muM), myricetin (0.39 muM), procyanidin B2 (PB2, 4.5 muM), and resveratrol (65.7 muM) were potent topoisomerase II catalytic inhibitors present in TP-4 from grape cell culture. Synergistic interaction between myricetin and resveratrol (at a molar ratio of …
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Vliv dihydromyricetinu a myricetinu na vybrané biotransformační enzymy
… V této diplomové práci byl zkoumán vliv dihydromyricetinu (potenciální lék závislosti na alkoholu) a jemu strukturně podobnému myricetinu na aktivitu cytochromu P450 2E1 (CYP2E1) a N-acetyltransferas 1 a 2 (NAT1/2). Sledován byl jak vliv premedikace potkanů těmito flavonoidy na expresi a …
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Multidrug resistance-associated protein 2 (MRP2) and oxaliplatin transport
… were reversed by inhibition of MRP2 with myricetin. Studies of human gastrointestinal cancer cell lines demonstrated that MRP2-mediated deficits in cellular accumulation of oxaliplatin-derived platinum were observed in HepG2 and PANC-1 cells (0.14- and 0.34-fold difference relative to …
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Small Molecule Inhibitors of HPV16 E6
… allowed us to select the two best candidates, myricetin and 6,7-dihydro-1H-imidazo[4,5-c] pyridine-6-carboxylic acid (DIPC), for further testing. Both compounds significantly and specifically inhibited the ability of E6 to bind in vitro to both caspase 8 and to E6AP, the protein that mediates …
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ΜΕΛΕΤΗ ΤΩΝ ΧΗΜΙΚΩΝ ΣΥΣΤΑΤΙΚΩΝ ΤΟΥ ΦΥΤΟΥ CYCLAMEN GRAECUM L
… VICENIN-2, KAEMPFEROL, QUERCETIN, MYRICETIN AND FOUR FLAVONOIDS IN SMALLER AMOUNTS WHICH PRESUMABLY CAN BE IDENTIFIED TO WERE GOSSYPETINE-7-METHYL ETHER, 3',4',DI-04-ISOFLAVONE 7 METHYL ETHER, 8-OH- E. SOME TUBER EXTRACTS HAVE BEEN STUDIED FOR ANTICANCER ACTIVITY USING MICE IN WHICH …
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Small Molecules as Amyloid Inhibitors: Molecular Dynamic Simulations with Human Islet Amyloid Polypeptide (IAPP)
… quercetin, dihydroquercetin, epicatechin, and myricetin. Contacts between Phe23 residues are critical to oligomer formation, and small-molecule contacts with Phe23 are a key predictor of β-strand reduction. Structural properties influencing the ability of compounds to disrupt Phe23-Phe23 …
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Functionality of Azadirachta indica A. Juss (neem) in beverages
… LC-ESI-MS/MS to identify specific flavonols- myricetin, quercetin and kaempferol in neem leaves, which were present in greater quantities in neem than in these teas. These flavonols have been known to impart neem its anti-diabetic property and therefore, its identification and quantification …
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In vitro-Untersuchungen zu Inhaltsstoffen von Hypericum perforatum L. sowie topische Anwendung von Hypericum perforatum-Extrakten bei der Atopischen Dermatitis
… Substanzen wie Biapigenin, Amentoflavon, Myricetin, Epicatechin, Hyperosid, Kaffeesäure und Chlorogensäure zeigten keine therapeutisch wirksame Proliferationshemmung im Proliferationsessay mit 3H-Thymidin oder im BRDU-Elisa. Wir haben den Apoptosemechanismus, der durch Luteolin an …
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Evaluation of the antioxidant activity of extracts and flavonol glycosides isolated from the seed coats of coloured beans (Phaseolus vulgaris L.)
… the 3-O-glycosides of kaempferol, quercetin, and myricetin. Pinto beans contained kaempferol 3-O-glycosides, while light and dark red kidney beans contained quercetin 3-O-glycosides. In addition, we reported the presence of a flavonol triglycoside for the first time in dry bean seed coats. …
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Effects of malting and dehulling on the functional structural antioxidant properties of Bambara Groundnut (Vigna Subterranean) flour
… Bambara groundnut, with quercetin-3-O-glucoside, myricetin, and catechin the most common metabolites in processed BGN flours. Dehulling and malting are useful traditional methods for modifying BGN flours with different techno-functional, structural, nutritional, and protein-digestibility …