Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Myocilin"”.
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Use solid-state NMR to study the molecular structures of disease-associated peptide aggregates
… from the residue sequence of glaucoma-associated myocilin. An amyloid model of stacked U-shaped antiparallel β-sheets was successfully built by NMR-constrained molecular dynamic (MD) simulation. These structural studies demonstrate the power of ssNMR in characterizing different forms of protein …
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Magnetic Steering to Save Sight: Trabecular Meshwork Cell Therapy as a Treatment for Primary Open Angle Glaucoma
… capabilities of two types of cells in a mutant myocilin mouse model of ocular hypertension, characterizing the morphological and functional benefits of the treatment. The central hypothesis of this work is that an optimized magnetically-driven TM cell therapy can lead to long-term clinically …
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Uniaxially aligned, porous collagen-GAG scaffolds for in vitro modeling of trabecular meshwork
… to glucocorticoids by overexpressing the protein myocilin.