Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 259 for “"Myocardium"”.
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Estrogen action in the myocardium
… current knowledge on the role of estrogen in the myocardium itself rather scarce. Functional estrogen receptor-alpha as well as -beta have recently been identified in the myocardium, making the myocardium an estrogen target organ. The focus of this thesis was 1) to investigate the role of estrogen …
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Tumor suppressor pathway in myocardium
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Backscatter and Attenuation Characterization of Ventricular Myocardium
… quantitative ultrasonic measurements of the myocardium in fetal hearts and adult human hearts with the goal of studying the physics of sound waves incident upon anisotropic and inhomogeneous materials. Ultrasound has been used as a clinical tool to assess heart structure and function for …
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Quantitative and Qualitative Assessment of the Myocardium at Risk
… an acute coronary occlusion is the size of the myocardium subjected to ischemia. Identification and quantification of this so-called myocardium at risk in the acute phase of ischemia has been difficult in patients with conventional methods, such as myocardial perfusion single-photon emission …
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A Putative Cytosolic Saxitoxin Binding Protein in Frog Myocardium
Approximately 20% of the protein in sarcolemma vesicles prepared from the hearts of the North American frog Rana pipiens pipiens is solubilized by a 96 hour dialysis of the vesicles against a low ionic strength solution of ethylene-diaminetetraacetic acid (EDTA) at pH 8.5. All of the polypeptides …
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Cellular pathways of angiotensin II signalling in the hypertrophic myocardium
… of angiotensin II (ATII) on the hypertrophic myocardium. The significance of this work is both biological and clinical: biological, because ATII has direct effects on the normal heart muscle and the intracellular signalling pathways activated by ATII are not fully understood. Clinical, because …
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Localized HB-EGF signaling and Connexin43 decrease in the myocardium
… circuit in the extracellular space within the myocardium, revealing the critical nature of the local microenvironment in intercellular signaling. In vitro studies demonstrated that HB-EGF acts as an autocrine growth factor in cultures of rat neonatal cardiomyocytes. However, in vivo experiments …
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Electrical modeling of myocardium and development of advanced pacing techniques
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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The Relationship between Ephaptic Coupling and Excitability in Ventricular Myocardium
Introduction: Excitability in cardiomyocytes is dependent on the subthreshold current required to raise transmembrane potential to the activation threshold and subsequent recruitment of voltage gated sodium channels to trigger an action potential. Conduction in cardiomyocytes is dependent on the …
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In vitro metabolism of atrial and ventricular myocardium: effect of ouabain
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Novel Phenotyping of the Myocardium by Diffusion Tensor Cardiovascular Magnetic Resonance
Novel Phenotyping of the Myocardium by Diffusion Tensor Cardiovascular Magnetic Resonance Dr Zohya Khalique Introduction The heart has a complex microarchitecture facilitating its function. The helical cardiomyocyte arrangement (left-handed in the epicardium through to right-handed in the …
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Exchange of Potassium Between Blood and Tissue in the Canine Myocardium
Made available in DSpace on 2014-12-09T18:53:05Z (GMT). No. of bitstreams: 1 6901335.pdf: 5762083 bytes, checksum: 8ec75b3e720030b583740530474037e6 (MD5) Previous issue date: 1968
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Investigating the coordination of cardiac conduction and repolarization in ventricular myocardium
… by the degree of cell-cell coupling in the myocardium, but instead is driven by endogenous gradients of action potential duration within the tissue. Taken together, these data demonstrate ways in which both conduction and repolarization are sensitive to modulations of EpC, though we also …
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The Temporal Nature of Ectopic Activity in Guinea Pig Ventricular Myocardium
The temporal nature of ectopic activity is important to elucidating the mechanisms that can lead to arrhythmogenesis. However, challenges remain in distinguishing between ectopic and non-ectopic beats. A new methodology was developed and validated to distinguish between beat types. Rapid pacing was …
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The Effects of Cocaine and Ecstasy on Cardiac Myocytes and the Intact Myocardium
… that cocaine and ecstasy are detrimental to the myocardium of the heart, causing several disturbances with pathological potential.</p>
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Calculating 3D intramyocardial strain tensors in a single slice of myocardium using MRI
… 3D strain tensor field for a single slice of myocardium is proposed.
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Microstructural non-linear finite-element analysis of rat myocardium with hydrogel biomaterial inclusions
… confocal mi croscopy imaging data of rat myocardium. The reconstructed mesh did not necessitate idealisations of the cardiac tissue structure or the distribution of the hydrogel injectate. To investigate the mechan ical response of the microstructure, under the assumption that both the …
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Veränderungen der Calcium-Homöostase als mögliche Ursache einer linksventrikulären Funktionsstörung im humanen "hibernating myocardium"
… Anfang der 80er Jahre den Begriff "hibernating myocardium" als ein Stadium persistierender Beeinträchtigung myokardialer und linksventrikulärer Funktion in Ruhe, aufgrund eines chronisch reduzierten koronaren Blutflusses. Die funktionelle Beein-trächtigung kann entweder durch Verbesserung des …
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A computational study of post-infarct mechanical effects of injected biomaterial into ischaemic myocardium
… passive and active behaviour of the ischaemic myocardium at each time point. The geometry of the LV with the fibrotic infarct was adjusted to represent the wall thinning that occurs during LV post-MI remodelling. Hydrogel injection was modelled as layers with material properties differing from …
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