Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Myeloid Differentiation Factor 88"”.
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Expression and Function of Toll-Like Receptor 2 and 4 in Human Melanocytes
… TLR2, TLR4 and their adaptor proteins, CD14 and myeloid differentiation factor-88 (MyD88) was shown by RT-PCR. Protein expression and localization of TLR2, TLR4 and CD14 were detected by western blot, flow cytometry and immunocytochemistry. Lipopolysaccharide (LPS) was used as microbial …
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A transcriptomic approach for studying the activation of dendritic cells in response to mycobacterial infections
… M. tuberculois infection. Interferon Regulatory Factors (IRFs) and NFkB (Nuclear Factor kappa B) appear to be the principal transcription factors involved in regulating the cellular responses in M. tuberculosis infected BMDCs. It has been found that IRFs can function independent of the adaptor …
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Chlamydia pneumoniae, Toll-like Receptors and Pathogenesis of Atherosclerotic Heart Disease
… be sufficient to induce foam cell formation. In myeloid differentiation factor 88 (MyD88)-deficient macrophages, TLR4 and TLR3 agonists each induce foam cell formation in the absence of exogenous LDL, suggesting that MyD88-mediated signaling interferes with MyD88-independent foam cell formation. …
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MyD88-Mediated Signaling in Protective Immunity against an Attenuated West Nile Virus Infection
… protective immunity. Toll-like receptor (TLR) 7/myeloid differentiation factor 88 (MyD88)-mediated signaling pathways protect host against wild-type WNV infection. Both MyD88-/- and TLR7-/- mice had reduced effector T cell functions compared to wild-type mice following NS4B-P38G mutant infection. …
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Roles of MAVs and MYD88 in Innate and Adaptive Immune Responses to Respiratory Syncytial Virus
… signal through the adaptors TRIF (TLR3, 4), MyD88 (TLR4, 7/8, 9), and MAVS (RIG-I). The innate response serves to limit viral spread and to activate adaptive immune responses which eventually clear the infection. We dissected the contribution of TLR- and RLR- mediated recognition in the host …
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Protective Role of Mesenchymal MyD88 Signaling Under Homeostasis and Initiation of Inflammation in the Colon
… host cells, including stromal cells, requires myeloid differentiation factor 88 (MyD88). Overall, MyD88-dependent interactions between the microbiota and the host is reported to contribute to epithelial barrier restoration via repositioning of mesenchymal stromal cells producing COX-2/PGE2 …