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Showing 1 to 2 of 2 for “"Mycolactone"”.
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High Resolution Mass Spectrometry (HRMS) Based Investigation of Small Molecule, Bioactive Secondary Metabolites as Probes in the Examination of Bacterial Resistance and Virulence
<p>The widespread availability of antimicrobial chemotherapeutics over the last half of the twentieth century has offered dramatic increases in life expectancy. Unfortunately, many pathogenic agents are exhibiting ever increasing resistance to many frontline antibiotics. New chemotherapeutic agents …
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The Use of Spectroscopic Techniques in the Characterization of Mycobacterial Metabolites
… better analyzed through an MS-based approach. Mycolactones of <em>M. ulcerans</em> and other closely related species are good examples for such metabolites and in this work we have demonstrated the utility of MS as a tool for screening for mycolactones from both bacterial culture and tissue …