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Showing 1 to 20 of 58 for “"Mycobacterium avium"”.
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Macrolide Resistance in Mycobacterium avium
Mycobacterium avium isolates resistant to clarithromycin and azithromycin have been recovered from patients undergoing antibiotic therapy. Comparison of DNA fingerprints of sensitive and resistant isolates showed that resistance resulted from mutation of the original, sensitive isolate in five of …
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Disinfectant Susceptibility of Mycobacterium avium
Mycobacterium avium, an opportunistic human pathogen, infects between 25 and 50% of advanced-stage acquired immuno-deficiency syndrome (AIDS) patients in the United States. M. avium has been isolated from many environmental sources including: natural waters, soils, and aerosols. M. avium has also …
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Plasmid-influenced changes in Mycobacterium avium catalase activity
A virulent Mycobacterium avium strain, LR25, which carries 3 plasmids (18, 28, and 165 kb) and grows at 43°C was compared to its plasmid-free, avirulent segregant, strain LR163, to investigate the basis for the latter's inability to grow at 43°C. The failure of mid-log phase cultures of strain …
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Survival Of Mycobacterium Avium Subspecies Paratuberculosis In The Pol
Mycobacterium avium subspecies paratuberculosis (map) is an intracellular pathogen that is known to parasitize macrophages and monocytes. Map infiltrates gastrointestinal tract host tissue where it is the known etiological agent of johne's disease in ruminants and implicated in the etiology of …
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Proteomic analysis of the Mycobacterium avium-containing phagosome membrane
Pathogenic mycobacteria, like [Mycobacterium tuberculosis] M.tb and Mycobacterium avium (M.av), reside intracellularly in phagosomes where they are able to survive, because they block the process of phagosome maturation. ... An approach of characterizing M.av-containing phagosomes in terms of cell …
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Action of clofazimine on Mycobacterium avium and Mycobacterium intracellulare
… against a variety of mycobacteria including M. avium. The presence of clofazimine in growth medium resulted in higher carotenoid pigmentation in M. avium cells. Carotenoid pigments have been shown to quench superoxide radicals supporting the hypothesis that pigmentation possibly protected cells …
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Nitrate- and Nitrite-Reductase Activities in Mycobacterium Avium A5
Mycobacterium avium is human and animal opportunistic pathogen responsible for disseminated disease in immunocompromised patients. Mycobacteria have a capacity to adapt to the environmental conditions by inducing enzyme activities and altering their metabolism. M. avium A5 cells were grown in a …
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Epidemiology of <i>Mycobacterium avium</i> complex infecting AIDS patients
Organisms of the <i>Mycobacterium avium</i> complex cause disseminated infections in 25 to 50 % of patients with AIDS. To assess the likelihood of exposure to M avium, we attempted to recover M. avium complex from environmental samples in geographical areas (Boston, Massachusetts; Hanover, New …
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Development of Drug Loaded Nanoparticles for Treatment of Mycobacterium avium Infection
… the world's population is latently infected with Mycobacterium tuberculosis and about 4 million people die from the disease annually worldwide. Although treatment with antimicrobials can be curative, many people fail to complete the prescribed therapeutic regimen which can increase the risk of …
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Relationship of plasmids in Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum
Bacteria of the <i>Mycobacterium avium, M. intracellulare, and M. scrofulaceum</i> group (MAIS) are opportunistic human pathogens and widespread in the environment. The first objective of this study was to demonstrate that plasmids from clinical isolates are closely related to plasmids from …
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Survival strategies of Mycobacterium avium subsp. paratuberculosis in a variety of microenvironments.
Mycobacteria, specifically Mycobacterium avium subsp. paratuberculosis (MAP), are extreme strategists and as a rule live by deception. Mycobacteria represent a group of closely related acid-fast bacilli that encompass a wide-range of host tropisms and diseases. Mycobacteria can be divided into two …
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Characterization of Cadmium susceptibility in Mycobacterium avium, Mycobacterium intracellulare and Mycobacterium scrofulaceum
… and sequestering by protein were measured in two Mycobacterium scrofulaceum strains differing in their susceptibility to that toxic heavy metal cation. Cadmium accumulation was energy-dependent and temperature-sensitive. The tolerant strain had lower K<sub>m</sub> and V<sub>max</sub> values than …
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Investigation of the host-mediated proteolytic response to pulmonary Mycobacterium Avium Complex infection
… NTM infection is increasing rapidly. In the UK, Mycobacterium avium complex (MAC) is the most common pulmonary NTM infection outside the setting of cystic fibrosis lung disease. Patients with pulmonary MAC infection develop cavitating lung disease or nodular bronchiectasis. Prolonged treatment is …
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Transmission Dynamics Of Mycobacterium Avium Subspecies Paratuberculosis In Closed Dairy Herds In The Us
… present work focused on within farm dynamics of Mycobacterium avium subsp paratuberculosis (MAP) infection on commercial US dairies. We focused on using deterministic mathematical models informed by molecular epidemiology and analysis of longitudinal data to evaluate current assumptions of MAP …
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Age and Dose Dependent Susceptibility to Mycobacterium avium subspecies paratuberculosis Infection in Dairy Calves
Mycobacterium avium subspecies paratuberculosis (MAP) causes Johne’s disease (JD), a chronic enteritis in ruminants. Control programs focus on prevention of infection of susceptible individuals: calves < 6 months of age. However, this age-cut-off for susceptibility is not well supported …
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Investigation of catalase and superoxide dismutase from Mycobacterium avium, M. intracellulare and M. scrofulaceum
… activity was detected in cell-free extracts of Mycobacterium avium, M. intracellulare and M. scrofulaceum (MAIS). The M. scrofulaceum isolates had the highest catalase activity, while both M. avium and M. intracellulare had significantly lower activities. The percentage of catalase activity …
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Adherence and Biofilm Formation of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus in household plumbing
… associated risk factors. Three species of NTM, Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus, were examined for adherence and biofilm formation on surfaces common to household plumbing systems, including glass, copper, stainless steel, polyvinyl chloride, and …
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Effect of growth in biofilms upon antibiotic and chlorine susceptibility of Mycobacterium avium and Mycobacterium intracellulare
Mycobacterium avium and Mycobacterium intracellulare are environmental opportunistic pathogens whose source for human infection is water and soil. M. avium and M. intracellulare cause pulmonary infections (tuberculosis) in immunocompetent individuals and bacteremia in immunodeficient individuals …
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Characterization of Mycobacterium avium cytoplasmic membrane proteins with an emphasis on the major cytoplasmic membrane protein
Proteins of the cytoplasmic membrane of Mycobacterium avium were investigated to identify those which were: (1)intrinsic or extrinsic, (2) attached to the cell wall, (3)surface accessible and (4) excreted. In addition sera containing anti-cytoplasmic membrane proteins were obtained and preliminary …
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Creating a Marked Mycobacterium avium subsp. paratuberculosis Vaccine Strain and Detecting Marker-Specific Immune Responses in Calves
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of Johne’s disease, a chronic, contagious granulomatous enteritis with a high global prevalence in dairy cattle. This disease causes significant economic loss in the dairy industry and has been challenging to control due to …
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