Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 597 for “"Mycobacterium"”.
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Relationship of plasmids in Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum
Bacteria of the <i>Mycobacterium avium, M. intracellulare, and M. scrofulaceum</i> group (MAIS) are opportunistic human pathogens and widespread in the environment. The first objective of this study was to demonstrate that plasmids from clinical isolates are closely related to plasmids from …
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Characterization of Cadmium susceptibility in Mycobacterium avium, Mycobacterium intracellulare and Mycobacterium scrofulaceum
… and sequestering by protein were measured in two Mycobacterium scrofulaceum strains differing in their susceptibility to that toxic heavy metal cation. Cadmium accumulation was energy-dependent and temperature-sensitive. The tolerant strain had lower K<sub>m</sub> and V<sub>max</sub> values than …
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Adherence and Biofilm Formation of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus in household plumbing
… associated risk factors. Three species of NTM, Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus, were examined for adherence and biofilm formation on surfaces common to household plumbing systems, including glass, copper, stainless steel, polyvinyl chloride, and …
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Action of clofazimine on Mycobacterium avium and Mycobacterium intracellulare
Clofazimine is a member of the phenazine pigment family which has been successfully used in chemotherapy against a variety of mycobacteria including M. avium. The presence of clofazimine in growth medium resulted in higher carotenoid pigmentation in M. avium cells. Carotenoid pigments have been …
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Mycobacterium tuberculosis metallomics
… compounded by the rise of drug-resistant Mycobacterium tuberculosis (Mtb) strains, which necessitate the development of novel therapies or improvement of existing ones. Nanotechnology has gained prominence in the biomedical field, yet its application in TB treatment remains underexplored. …
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Tenosinovitis infecciosa por Mycobacterium Tuberculosis
… frecuente de manifestación extrapulmonar del Mycobacterium tuberculosis, etiología que por su comportamiento clínico y paraclínico puede confundir al examinador retardando su proceso diagnóstico Este artículo presenta el caso de un paciente masculino de 63 años, diestro, cesante, sin …
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Macrolide Resistance in Mycobacterium avium
Mycobacterium avium isolates resistant to clarithromycin and azithromycin have been recovered from patients undergoing antibiotic therapy. Comparison of DNA fingerprints of sensitive and resistant isolates showed that resistance resulted from mutation of the original, sensitive isolate in five of …
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Glyoxylate Metabolism in Mycobacterium smegmatis
<p>Much has been learned about Mycobacterium tuberculosis, the causative agent of tuberculosis, "the great white plague," since the bacterium was isolated and initially characterized by Robert Koch over a century ago. Over the last decade, new genetic tools for manipulation of the bacterium have …
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Disinfectant Susceptibility of Mycobacterium avium
Mycobacterium avium, an opportunistic human pathogen, infects between 25 and 50% of advanced-stage acquired immuno-deficiency syndrome (AIDS) patients in the United States. M. avium has been isolated from many environmental sources including: natural waters, soils, and aerosols. M. avium has also …
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Characterization of protein secretion in Mycobacterium leprae using phoA fusions in Escherichia coli and Mycobacterium smegmatis
Complete sequencing and annotation of the M. leprae genome has provided new information related to proteins constituting its hypothetical proteome. Since M. leprae can not be grown in vitro, novel approaches are needed to determine which proteins are expressed during infection and whether these …
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Effect of growth in biofilms upon antibiotic and chlorine susceptibility of Mycobacterium avium and Mycobacterium intracellulare
Mycobacterium avium and Mycobacterium intracellulare are environmental opportunistic pathogens whose source for human infection is water and soil. M. avium and M. intracellulare cause pulmonary infections (tuberculosis) in immunocompetent individuals and bacteremia in immunodeficient individuals …
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Functional Genome Analysis of Mycobacterium tuberculosis
… DNA-Arrays, die sämtliche offenen Leseraster von Mycobacterium tuberculosis repräsentieren, wurde eine funktionelle Genom-Analyse des Erregers der Tuberkulose durch geführt. Ein Genom-Vergleich von Mitgliedern des M. tuberculosis-Komplexes wies zusätzlich zu den bekannten Deletionen weitere, …
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Glucan metabolism in mycobacterium and streptomyces
α-Glucans are typically used for carbon storage in bacteria, however, they are also a major component of the mycobacterial capsule. In this context, glucans have been implicated in the evasion of recognition by macrophages. A novel α-glucan synthesis pathway, called the GlgE pathway, is a potential …
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Developing novel therapies for Mycobacterium abscessus
Mycobacterium abscessus (M. abscessus) is a rapid growing non-tuberculous mycobacteria (NTM) that is increasingly recognised as a major pathogen owing to its inherent resistance to a wide range of the currently available antibiotic therapies. In particular, it causes problems in patients with …
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Improving antibiotic therapy for Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is a slow-growing bacterium that causes tuberculosis (TB), which is a leading cause of death from an infectious disease worldwide. The emergence of drug-resistant strains has made TB increasingly difficult to treat, especially in individuals with weakened immune …
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The Mycobacterium tuberculosis protein O-phosphorylation landscape
… protein kinases (STPKs) is identified. Mycobacterium tuberculosis (Mtb) in particular has a larger repertoire of both STPKs and O-phosphoproteins than most bacteria, suggesting a more prevalent role of STPKs in Mtb. Many studies have identified individual STPK functions and substrates, …
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Tackling Mycobacterium abscessus infection in Cystic Fibrosis
Mycobacterium abscessus is an emerging pathogen with infections increasing worldwide, especially among Cystic Fibrosis (CF) patients. During my PhD, I studied key aspects of the biology of M. abscessus spp.; particularly, I studied host-pathogen interactions, antimicrobial resistance mechanisms, …
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