Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Myc proteins"”.
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Targeting the N-myc oncoprotein using nanobody technology
The myc family of oncogenic transcription factors, which includes c-myc, N-myc and L-myc, control major cellular processes such as proliferation and differentiation by integrating upstream signals and orchestrating global gene transcription. They do this largely through dimerising with Max, which …
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Characterization of the Paraneoplastic Cerebellar Degeneration Antigen Cdr2
… a yeast two-hybrid screen, we have identified c-Myc as a cdr2-binding protein. Immunohistochemical analysis of cerebellar cortex revealed that cdr2 and c-Myc colocalize exclusively to the cytoplasm of Purkinje neurons. We have found that the full length cdr2 and c-Myc proteins interact in vitro, …
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Myc-Funktion im Zellwachstum und Identifikation von neuen Myc-regulierten Genen in B-Zellen
Die Überproduktion des Myc-Proteins ist eine Ursache für die Entstehung einer großen Anzahl von humanen Tumoren. Die Erforschung der Myc-Funktionen ist daher ein wichtiges Ziel der Tumorbiologie. Mit einem neuartigen Zellsystem wurde in dieser Arbeit die Rolle von Myc für das Wachstum von Zellen …
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Characterization of a plant-specific membrane-tethered myb transcription factor in Arabidopsis thaliana
… all living organisms. Transcription factors are proteins that can regulate gene expression through direct interaction with DNA and protein-protein interactions. The majority of transcription factors are localized to either the cytosol or the nucleus where they can easily access DNA. In contrast, …