Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Mutagenesis, Insertional"”.
-
A Novel Transgenic Rat Model for the Study of Germ Cell Biology
With over one million publications in scientific journals, the rat is a very important biological model in science. Unfortunately, since the introduction of genetic manipulation technology in the mouse, extension of this technology to the rat has proven to be very difficult. In an attempt to …
-
Understanding Autism Pathology: Insights from Genetic Mouse Model Manipulation of KCTD13 and SHANK3
Copy number variations (CNVs) contribute to the etiology of Autism Spectrum Disorders (ASDs). Deletions/duplications in human chromosomal region 16p11.2 are frequently associated with ASD and other neurodevelopmental disorders. Specific genes within this region may be important for determining …
-
Synergism of Gingipains in Endothelial Cell Adhesion Disruption and Apoptosis
<p>The presence of <em>Porphyromonas gingivalis</em>in the periodontal pocket and the high levels of gingipain activity detected in gingival crevicular fluid could implicate a role for gingipains in the destruction of the highly vascular periodontal tissue. To explore the effects of these proteases …