Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"Muscle hypertrophy"”.
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Genes with Physiological Roles in Callipyge Muscle Hypertrophy
… an excellent model to study genes regulation in muscle growth since the up-regulation of DLK1 and/or RTL1 results in extreme postnatal muscle hypertrophy in loin and hindquarters. DLK1 and/or RTL1 are the primary inducers of muscle hypertrophy due to the inheritance model for the callipyge …
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Molecular Mechanisms of Growth Hormone Induced Muscle Hypertrophy
… (3) evaluate the presence of oncogene mRNA in muscles from rats bearing GH$\sb{3}$ tumors and in myogenic cell lines.
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Altering Muscle Hypertrophy and Fat Accumulation in Myostatin Null Mice
Myostatin is a negative regulator of muscle growth. Loss of myostatin function results in a dramatic phenotype in several species including cattle, mice, dogs and humans. Myostatin mutants exhibit wide-spread hypermuscularity and decreased fat accumulation. Though the phenotype of myostatin mutant …
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EFFECTS OF EXERCISE PRECONDITIONING ON MUSCLE HYPERTROPHY AND MITOCHONDRIAL REMODELING FOLLOWING THE SUBSEQUENT RESISTANCE TRAINING
… with a previous training history acquire muscle volume at an accelerated rate. This phenomenon may be attributed, in part, to the myonuclear enrichment resulting from the proliferation of muscle progenitor cells, which promotes essential protein synthesis following subsequent muscle …
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The effect of dietary creatine supplementation on compensatory muscle hypertrophy and performance characteristics of specific fiber types
… supplementation on compensatory muscular hypertrophy and electrically stimulated performance of those muscles. Thirty-six rats were divided evenly into six groups. Two groups were surgical controls, two groups had the tibialis anterior ablated, to hypertrophy the extensor digitorum longus …
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Involvement of Platelet-Derived Growth Factor, PDGF Receptor Signaling, Focal Adhesion Kinase and SRC in Pressure-Induced Vascular Smooth Muscle Hypertrophy
… the early events in the vascular smooth muscle response to acute hypertension and to identify mediators involved in long-term hypertensive remodeling.</p> <p>In the acute phase of hypertension we targeted cell surface integrin and growth factor receptors thought to be mechanically …
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The Effect of Hyperthermic Whole Body Heat Stimulus (Sauna) on Heat Shock Protein 70 and Skeletal Muscle Hypertrophy in Young Males during Weight Training
… Finnish steam sauna is theorized to aid skeletal muscle hypertrophy by stimulating Heat Shock Protein 70 (HSP70), which acts as a molecular chaperone to the folding of functional skeletal muscle. The aim of this study was to investigate if stimulating HSP70 by using a sauna (45 – 50 ͦC, 80% …
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Association Between ACE Genotype and Skeletal Muscle Strength and Volume, and Their Response to Strength Training in Older Adults
… (ACE) gene with variability in the response of muscle strength and mass to strength training, though conclusions have been inconsistent across investigations. The purpose of this study was to investigate the possible association between ACE genotype and skeletal muscle strength and volume, and …
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Energy metabolism in skeletal muscle: mechanistic insights into mitochondrial function and growth
Skeletal muscle metabolism is critical to understanding the efficiency of muscle growth for the global meat industry. As such, there are many contributing factors that can influence muscle growth yet there are still basic molecular mechanisms that remain unexplored. Specifically, the involvement of …
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Mechanisms Regulating Resistance Training Mediated Hypertrophy in Human Skeletal Muscle
… established that resistance training induces muscle hypertrophy, although the mechanisms and influence of biological sex are unclear. The extent of post-exercise myofibrillar protein synthesis (MyoPS), satellite cells (SC) and dietary amino acids to promote muscle hypertrophy have generally …
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Does Blood Flow Restriction Applied Post High-Load Exercise Augment Skeletal Muscle Growth Following Eight Weeks of Training?
… exercise has consistently been shown to augment muscle hypertrophy which has been attributed to metabolic accumulation. It remains unknown, however, whether metabolites can augment muscle growth independent of further mechanical tension, specifically when maintained post high-load training. …
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The genetic basis of human athletic performance
… and endurance performance, skeletal and cardiac muscle hypertrophy and performance in power associated sporting events. The nitric oxide synthase (ecNOS) G894T polymorphism is associated with endurance training induced decreased submaximal diastolic blood pressure and nitric oxide is a direct …
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Gene expression profiling of myostatin null mice
Increasing muscle growth is beneficial to the meat animal industry and for biomedical research. Altering myostatin function and administration of β-adrenergic agonists, such as clenbuterol, enhances muscle growth. However, it is unclear whether the mechanisms of these effects converge in a single …
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Effects of physical activity levels and nutritional intake on skeletal muscle protein turnover and cellular signaling
Loss of muscle mass is common in many clinical conditions such as cancer, AIDS, burns and paralysis as well as in aging. Decreased muscle mass can contribute to many other complications and co-morbidities related to diseases, trauma and aging including overall weakness, immobility, increased risk …
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Pax3 expression in satellite cells of avian skeletal muscle spindles during normal development and with experimental muscle overload
… embryonic somites, which gives rise to skeletal muscle. Following myogenesis, Pax3 expression is mostly down-regulated and becomes restricted to a few satellite cells (SCs) of select mature muscles. SCs are activated to form new myonuclei during muscle hypertrophy, regeneration and repair. …
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Stem-Cell Like PDGFR? Cells are Induced in Chronic Intestinal Partial Obstruction
… tract harbors a wide array of smooth muscle cells, motor neurons, and epithelial and stem cells. This makes it an attractive model system for the study of regeneration following mechanical injury. This project investigated the regenerative capacity of the gut by injuring the murine …
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Impacto da hipovitaminose D em pacientes adultos asmáticos: uma revisão da literatura
… edema, exaggerated mucus production and smooth muscle hypertrophy. It has several causal factors that can aggravate it, and a more current proposal is that poor immunological regulation due to hypovitaminosis D may be one of those responsible for its aggravation. Objective: To identify if there …
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Creating a Standardized Program To Resistance Train The Muscles Of The Head and Neck
… protocol to strengthen the head and neck muscles exists and no systematic study of increase in neck musculature attributed to such a protocol is documented. Thus, this study will produce a standardized methodology for the reduction of concussive and subconcussive forces, laying the …
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mTOR Signaling in Cellular Growth and Skeletal Muscle Maturation
… S6K2, and for the regulation of skeletal muscle myotube growth. My results showed that S6K2 requires mTOR and its kinase activity for its activation. Amino acid and nuclear-cytoplasmic shuttling of mTOR were shown to be required for S6K2 activation. Skeletal myogenesis is a …
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