Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Muscle Paralysis"”.
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Osteocyte Activity and Skeletal Muscle Relative Gene Expression Profiling After Short-term Muscle Paralysis
… of disuse osteoporosis. Disuse models of muscle inactivity and immobilization, like the Botox model used in this study, result in changes in the bone microarchitecture, the mechanisms behind which are not fully understood. In a previous four-week Botox disuse study, skeletally mature 20- …
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Regulation of a two-pore K+ channel by multiple subunits in Caenorhabditis elegans
… complex that when misregulated leads to severe muscle paralysis in the nematode C. elegans. We cloned sup-9 and found it encodes a K+ channel of the recently discovered mammalian two-pore family of voltage-insensitive leak channels, suggesting that SUP-10 and UNC-93, along with multiple …
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Understanding Potassium Homeostasis Using Human and Mouse Genetic Models
… physiological functions, such as excitability of muscles and neurons, rely on stable extracellular potassium concentration. To maintain potassium homeostasis, endogenous factors including hormones and peptides regulate the activity of potassium transporters in many organs, especially skeletal …
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An implantable hydrogel for the delivery of cisplatin and the ex vivo neurotoxic, neuromyopathic and cardiotoxic activity of platinum-based anticancer drugs and macrocyclic drug delivery systems
… studied using the chick biventer cervicis nerve muscle preparation. Results showed that incubation of the nerve-muscle tissue with 300 μM of cisplatin caused statistically significant muscle paralysis to occur by decreasing the electrically stimulated muscle twitch response by 96 ± 4% (p = …
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Magnesium recurarisation differences between no reversal, neostigmine/glycopyrrolate reversal and sugammadex reversal of neuromuscular block in an in vivo rat model
… transmission is sufficient to produce skeletal muscle paralysis, a mechanism used to facilitate muscle relaxation during surgery. Residual neuromuscular block postoperatively has been found to be a major risk factor for postoperative complications. Sudden reinstatement of neuromuscular block …
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A central medullary circuit regulating REM sleep and pontine waves
… as hippocampal theta oscillations and skeletal muscle paralysis, which are interleaved with short-lived phasic events such as rapid eye movements, limb twitches, and spike-like pontine (P)-waves. Considered a key hallmark of REM sleep, P-waves are coupled with transient increases in theta power …
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Acute and Chronic Effects of Botulinum Toxin Type-A on the structure and Function of the Quadriceps Femoris Muscles of New Zealand White Rabbits
… disorders with the primary aim to relax spastic muscles, for example, in children with cerebral palsy, or following a stroke. Once injected, BTX-A prevents acetylcholine release at the motor nerve endings, thereby producing a dose-dependent muscle paralysis. Despite an exponential growth of …
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Skeletal adaptation to reduced mechanical loading
… We first examined the relative contribution of muscle and gravitational forces to the maintenance of skeletal health in mice, using botulinum toxin (BTX) to induce muscle paralysis and hindlimb unloading to eliminate external loading on the hindlimbs, alone and in combination. BTX led to greater …
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Skeletal adaptation to reduced mechanical loading
… We first examined the relative contribution of muscle and gravitational forces to the maintenance of skeletal health in mice, using botulinum toxin (BTX) to induce muscle paralysis and hindlimb unloading to eliminate external loading on the hindlimbs, alone and in combination. BTX led to greater …
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In Children and Elderly Patients, What are the Effects of General Anesthesia on Neurological Health Compared with Procedural Sedation?
… state of unconsciousness with amnesia, muscle paralysis, sedative, and analgesic features. It can be administered via inhalation or intravenously with rapid onset. General anesthesia can be manipulated easily throughout surgery and can keep a patient unconscious for prolonged periods of …
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Efectividad de la terapia ocupacional en pacientes con parálisis facial que presentan trastornos depresivos de ambos sexos entre las edades de 15 a 80 años, atendidos en el centro de rehabilitación integral de oriente de la ciudad de San Miguel; en el periodo comprendido de septiembre a noviembre de 2007
… the affected side of the face, tearing, facial muscle paralysis, being one of the causes that leads to the susceptibility of mild to moderate depressive disorders in individuals who present it . The main objective of this study was to verify the effectiveness of occupational therapy in patients …
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Closed Loop Control of Muscle Contraction using Functional Electrical Stimulation
… approach to treat patients with vocal fold paralysis using electrical stimulation is investigated throughout this research work. Functional Electrical Stimulation works by stimulating the atrophied muscle or group of muscles directly by current when the transmission lines between the central …