Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Muscle Mechanics"”.
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Skeletal Muscle Energetics and Mechanics: The Effects of Magnesium on Resting and Contracting Muscle as Studied by Phosphorus Magnetic Resonance Spectroscopy
… is known about the role of calcium in skeletal muscle mechanics and energetics, little is known about the role of magnesium, especially in intact muscle. This work studies skeletal muscle energetics and mechanics using MR spectroscopy (MRS) with particular reference to the role of magnesium. The …
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Effects of Actin-Myosin Kinetics on the Calcium Sensitivity of Regulated Thin Filaments
Activation of thin filaments in striated muscle occurs when tropomyosin exposes myosin binding sites on actin either through calcium-troponin binding or by actin-myosin (AM) strong binding. However, the extent to which each of these binding events contributes to thin filament activation remains …
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Construction and assessment of a computer graphics-based model for wheelchair propulsion
… analyses involving kinetics, kinematics, and muscle mechanics provide an opportunity to identify modifiable risk factors associated with wheelchair propulsion and upper limb overuse injuries that may be used toward developing prevention and treatment interventions. However, these analyses are …
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NOVEL ROLES FOR GRK2 IN METABOLIC HOMEOSTASIS AND SKELETAL MUSCLE PHYSIOLOGY
… is known about the role of GRK2 in skeletal muscle function and disease. In the first study of this dissertation, we generated a novel skeletal muscle specific GRK2 knockout (KO) mouse (MLC-Cre:GRK2fl/fl) to gain a better understanding of the role of GRK2 in skeletal muscle physiology. In …
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Interactions of Smooth Muscle Myosin Filaments with Actin and Myosin Light Chain Kinase: Insights into the Mechanics of Smooth Muscle Contraction
The functional form of smooth muscle myosin (SMM) within cells is the filament. Smooth muscle contraction is thick (myosin) filament-regulated by phosphorylation of the myosin regulatory light chain (RLC). Upon phosphorylation of Serine 19 of the RLC of SMM by myosin light chain kinase (MLCK), SMM …
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Modifiable risk factors of hamstring strain injury : assessment, performance and training
… currently unknown what is occurring within the muscle during the exercise and potential variations. Within Chapter 6, kinematic, EMG and in-vivo ultrasound imaging was performed, while 13 participants (10 males, 3 females) with resistance training experience, performed NHE variations (0, -20 and …
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Modelling of mechanosensitive morphogenesis and maintenance of cell structure: Application to musculoskeletal cells and tissues
… hold epithelial soft tissues as well as cardiac muscle together. The nucleation of clusters of adhesive molecules is the first step towards specialising the cells that contain them in order to develop and strengthen many of the structures in the body. It has recently been shown that they can …