Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"MurD"”.
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Investigation into peptidoglycan biosynthetic enzymes from the Lyme disease spirochete Borrelia burgdorferi
… Mur ligase, BB0585, to confirm its identity as a MurD ligase. These findings advance our understanding of cell wall biosynthesis in B. burgdorferi and highlight Mur ligases as potential targets for therapeutic intervention against Lyme disease.
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Metabolomic Analysis of Bacterial Cell Wall Intermediates Using LC-MS/MS: Peptidoglycan Pathway Response to Different Antibiotics
… at least three potential regulatory loops (GlmU, MurD and Ddl enzymes) within this pathway. Sub-MIC exposures to antibiotics demonstrated effects even at 1/8x MIC which strongly paralleled acute exposure changes. The effect of non-cell wall targeting inhibitors on PG pathway was also performed and …
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Structural And Functional Characterization Of Proteins Of Unknown Function (hp0495, Hp0100 And Hp1259) In Helicobacter Pylori
… The hp0495 gene is in an operon with mraY and murD, these two enzymes are involved in cell wall biosynthesis, suggesting that Hp0495 might be involved in regulating this process. There is also precedence for the involvement of EF-Tu in cell wall biosynthesis, supporting this hypothesis. </p> …