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Showing 1 to 1 of 1 for “"Munc18c, Syntaxin 4, SNARE, diabetes"”.
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Regulation of Exocytosis by Syntaxin 4-Munc18c Complexes
Type 2 diabetes involves defects in glucose-stimulated insulin secretion (GSIS) from the pancreatic beta cells in combination with defects in peripheral (muscle and adipose) tissue glucose uptake. Both GSIS and glucose uptake are regulated by Syntaxin 4 (Syn4)-Munc18c complexes. Importantly, …