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Showing 1 to 1 of 1 for “"Multistate equilibrium thermodynamics"”.
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Biophysical studies of the allosteric regulatory mechanism of Syk tandem SH2 domains interacting with immunoreceptor tyrosine-based activation motifs
… changes in the domain-domain coupling and multistate equilibrium thermodynamics of tSH2-ITAM interaction. These data suggested an entropic-allostery mechanism of Syk release from immunoreceptors. The new knowledge obtained from this work will help to explain the regulatory mechanism of Syk …