Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Multi-electrode array (MEA)"”.
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Characterization of spontaneous and evoked activity of mouse embryonic stem cell derived motor neurons using optogenetics and micro electrode array electrophysiology
… developing MN networks. The following work uses multi-electrode array (MEA) electrophysiology and optogenetics to characterize electrical activity of MNs differentiated from mouse embryonic stem (mES) cells. A customizable substrate integrated 60-electrode MEA chip was designed for this study. …
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The Emergence of Network Hyperexcitability and Functional Impairment in a Mouse Model of Alzheimer’s Disease
… Aβ oligomerisation — were evaluated utilising multi-electrode array (MEA) electrophysiological recordings. Ex vivo hippocampal slices, taken from 1- and 3-month-old AppNL-G-F mice, were challenged with increased [K+] in artificial cerebrospinal fluid (aCSF) superfusate to induce …
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The regulation of neuronal excitability by epilepsy-associated gene Nedd4-2
… the regulation of neuronal network excitability. Measured by a multi-electrode array (MEA) system, the spontaneous neuronal activity in Nedd4-2andi cortical neuron cultures was basally elevated compared to wild-type (WT) cultures. Subsequently, our data indicated that when pharmacologically …