Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"MuRF1"”.
-
Transcriptional Regulation of Neurogenic Atrophy-Induced Gene Expression by Muscle Ring Finger-1 and Myogenic Regulatory Factors
… and aging. The E3 ubiquitin ligases, MuRF1 and MAFbx, are induced under nearly all atrophy conditions and are believed to play a key role in protein degradation in atrophying muscle. However, the preliminary data described in this study provides new evidence that MuRF1 may also act as …
-
Regulation of Protein Degradation In The Heart By Amp-Activated Protein Kinase
… The ubiquitin ligases MAFbx /Atrogin-1 and MuRF1, key regulators of protein degradation, and AMPK activity are increased during nutrient deprivation. Pharmacologic and genetic activation of AMPK is sufficient for the induction of MAFbx/Atrogin-1 and MuRF1 in cardiomyocytes and in the heart …
-
Regulation of Protein Degradation In The Heart By Amp-Activated Protein Kinase
… The ubiquitin ligases MAFbx /Atrogin-1 and MuRF1, key regulators of protein degradation, and AMPK activity are increased during nutrient deprivation. Pharmacologic and genetic activation of AMPK is sufficient for the induction of MAFbx/Atrogin-1 and MuRF1 in cardiomyocytes and in the heart …
-
Effects of four weeks of daily soy or dairy milk ingestion on the exercise-induced proteolytic responses in plasma and skeletal muscle in a post-menopausal female population.
… mRNA expression of ubiquitin, E2, E3, atrogin-1, muRF1, calpain 1, and calpain 2. Although no significant group x time interactions were observed, a significant time effect was observed for plasma CK (p<0.0001) and muscle mRNA expression of E3 (p=0.04), atrogin-1 (p=0.02), and calpain 2 (p=0.04). …
-
Effects of 28 days of protein and amino acid supplementation and ankle immobilization on gastrocnemius muscle mass and strength and atrophy- and apoptosis-related gene expression in males.
… ubiquitin, 20S-HC2, 20S-HC3, E2, E3, atrogin-1, MuRF1, calpain 1, calpain 2, myostatin, TNF-α, and NF-κB. Results: Lower-leg girth decreased over time (p = 0.020), and increased the expression of several genetic variables, but there were no significant changes in the body composition or strength …
-
Growth Differentiation Factor 5 is a Paracrine Regulator of Sarcopenic Obesity
… D1, MyoD, MyoG), protein degradation (Atrogin, MuRF1) and inflammatory markers (IL-6, TNF-α) were assessed using RT-PCR for mRNA abundance. Results: There was a 62% and 30% (p<0.05) decrease of Gdf5 protein expression at 28 kDa and 55 kDa in the shRNA 1 group. The shRNA 2 and 3 groups had …