Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"MuLV"”.
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Recombination of endogenous and introduced kappa immunoglobulin gene sequences in the A-MULV transformant PD
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1985.
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Isolation of Moloney Leukemia Virus Temperature Sensitive Mutants, and the Characterization of a Temperature Sensitive Mutant Deficient in the Incorporation of Env Gene Proteins
… and revertants of Moloney leukemia virus (M-MuLV) and analysis of ts 7, an M-MuLV ts mutant isolated by Dr. P. K. Y. Wong are presented in this dissertation.
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… Both HIV and murine leukemia viruses (MuLVs) have evolved mechanisms to evade the action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous MuLVs evade mA3 inhibitory …
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… Both HIV and murine leukemia viruses (MuLVs) have evolved mechanisms to evade the action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous MuLVs evade mA3 inhibitory …
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Mechanism of TNF-α cytotoxicity in a leukemia virus transformation model
Abelson murine leukemia virus (A-MuLV)-induced transformation was investigated to determine whether cells not sensitive to TNF-α could be made sensitive to the cytolytic action of TNF-α when infected with this retrovirus. Mouse embryonic fibroblast cell line CL.7 was found to be relatively …
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Untersuchungen zur Rolle von zytotoxischen Molekülen bei der Immunabwehr gegen Retroviren
… Infektion von Mäusen mit dem nicht-pathogenen F-MuLV induzierte keine Produktion von zytotoxischen Molekülen in CD8+ T-Zellen. Die Infektion von „knockout“ Mäusen zeigte, dass F-MuLV von CD8+ T-Zellen über den Fas/FasL Weg kontrolliert wurde. Das pathogene Potential von Retroviren scheint also …
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Charakterisierung von funktionellen Oberflächenstrukturen des Hepatitis-B-Virus Nukleokapsids
… Ein mittels Transduktion von rekombinanten MuLV-Retroviren in die Zellen eingebrachtes verpackungskompetentes aber replikationsdefizientes HBV-Genom stellte die Hüllproteine zur Verfügung. Die erfolgreiche Transkomplementierung, d.h. Sekretion von virusähnlichen Partikeln, konnte durch PCR …
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VIRAL SAFETY EVALUATION OF BIOTECHNOLOGY PRODUCTS: DEVELOPMENT AND OPTIMIZATIONOF RELIABLE VIRAL CLEARANCE STRATEGIES
… of Eurofins, employing model viruses such as X-MuLV and MVM and combining chromatographic systems, filtration technologies, and advanced biological assays. This section provides an in-depth description of the methodologies adopted, the rationale behind the operational strategies, and a critical …
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Molekulare Analyse der Penetration von Foamyviren und Konstruktion und Charakterisierung von Adenovirus-Foamyvirus Hybridvektoren
… FV Spezies von lysosomotropen Agenzien mit MuLV oder Prototyp FV (PFV) Pseudotypen analysiert. Ähnlich wie bei Vesikuläres Stomatitis Virus Glykoprotein (VSV-G) Pseudotypen wurde die FV Env vermittelte Infektion von fast allen Agen-zien, die den endosomalen pH anheben, inhibiert. Allerdings …
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Structural Analyses of Murine Histocompatibility Antigens
… antiserum against the murine leukemia virus (MuLV) glycoprotein (gp70) and are therefore closely related to or identical with that viral protein. Further experiments suggest that factors such as viral antigens on the immunizing cells, aging, and general stimulation of the immune system may …