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Showing 1 to 2 of 2 for “"Mthk"”.
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Voltage-dependent gating at the selectivity filter of the MthK K+ channel.
… inactivation gating observed in MthK, a prokaryotic K+ channel that lacks a canonical voltage sensor. In single-channel recordings, I observed that open probability (Po) decreases with depolarization, with a half-maximal voltage of 96 ± 3 mV. This gating is kinetically distinct …
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Ion Selectivity and Gating in the NAK Channel
… in an open conformation much like that seen in MthK, making NaK the first channel for which both open and closed state structures are known. This is combined with a structural analysis of ion binding within the NaK selectivity filter, which reveals several interesting features that shed light on …