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Showing 1 to 2 of 2 for “"Mss116"”.

  1. Characterization of splicing mechanisms by single-molecule fluorescence

    … of its natural cofactor, the DEAD-box protein Mss116, using single-molecule fluorescence. Consistent with folding studies at very high magnesium concentrations, our single-molecule data show that Mss116 can promote the folding of group II introns under near physiological conditions <i>in …

    wayne-thes Repository record for Characterization of splicing mechanisms by single-molecule fluorescence (opens in a new tab)

  2. Genetic and biochemical analysis of a conserved DEAD-box helicase motif

    … amino acid motifs. Here we use S. cerevisiae Mss116p, a mitochondrial helicase required for efficient splicing of group I and group II introns, to probe the role of the conserved motif Va. We combine saturation mutagenesis, in vivo selection, and next-generation sequencing as part of a novel, …

    tdl Repository record for Genetic and biochemical analysis of a conserved DEAD-box helicase motif (opens in a new tab)