Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"MsbB"”.
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Induction of Long-Term Immune Responses to Protect Mice against Pneumonic Plague: Development and Testing of Novel Live-Attenuated Mutants of Yersinia pestis CO92
… Braun lipoprotein (Lpp), an acetyltransferase (MsbB), the attachment invasion locus (Ail), and/or the plasminogen-activator protease (Pla) creating the Δlpp ΔmsbB Δail and Δlpp ΔmsbB Δpla triple mutants of Y. pestis CO92. Another stain containing a modified version of the ail gene with …
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Heterologous Prime-Boost strategies using live-attenuated and viral vector vaccines to combat pneumonic plague
… pestis CO92 deleted for genes encoding Lpp, MsbB, and Ail. Ad5-YFV and LMA were either administered simultaneously (1-dose regimen) or 21 days apart in various order and route of administration combinations (2-dose regimen). The 2-dose regimen induced robust immune responses to provide full …
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Heterologous Prime-Boost strategies using live-attenuated and viral vector vaccines to combat pneumonic plague
… pestis CO92 deleted for genes encoding Lpp, MsbB, and Ail. Ad5-YFV and LMA were either administered simultaneously (1-dose regimen) or 21 days apart in various order and route of administration combinations (2-dose regimen). The 2-dose regimen induced robust immune responses to provide full …
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Construction and characterization of proteome-minimized OMVs from E. coli and their exploitation in infectious disease and cancer vaccines
… genes involved in the LPS biosynthetic pathway (msbB and pagP) were subsequently inactivated creating E. coli BL21(DE3)Δ60 which released OMVs with a substantially reduced reactogenicity. The exploitation of the two strains in vaccine applications was finally validated. We successfully …
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Generating Predictive Gene Expression Signatures for Alzheimer's Disease Using Postmortem Brain Tissue
… Mayo Clinic, and Mount Sinai Brain Bank (MSBB) to generate gene expression signatures from six brain regions affected at different stages of AD. These regions included the temporal and frontal lobes, as well as the cerebellum in which differential gene expression analysis identified genes …