Global ETD Search
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Showing 1 to 2 of 2 for “"Mpp6"”.
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Functional Consequences of Rna Exosome Complex Alteration By Conformational Changes and Cofactor Binding
… interaction. Moreover, another exosome cofactor, Mpp6, appears to mediate the interaction of the RNA exosome with other nuclear cofactors, and this function is redundant with Rrp6.</p> <p>This work demonstrates that there are two different RNA exosome conformations present <em>in vivo</em>, and …
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Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases
… interaction’ with nuclear cofactors (Rrp6, Mpp6, and Mtr4), where one of the interactions is required for the essential function of the exosome. Thus, analyzing disease variants in the budding yeast model provides important insights into RNA exosome defects caused by patient-derived variants …