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Showing 1 to 2 of 2 for “"Mouse organogenesis"”.

  1. Mechanisms Controlling the Segregation of Mitochondrial DNA Heteroplasmy

    … in place, I set out to study the heteroplasmy of mouse brain- and spleen-derived populations. In this endeavour, I made use of two novel mouse models that carry a mutation on mitochondrial-tRNA Alanine (mt-Ta), m.5019A>G and m.5024C>T. Recording single cell heteroplasmy values at different …

    cambridge Repository record for Mechanisms Controlling the Segregation of Mitochondrial DNA Heteroplasmy (opens in a new tab)

  2. Studying early development using droplet single-cell RNA sequencing

    … single-cell RNA-sequencing timecourse atlas of mouse development between embryonic days 6.5 and 8.5. I also performed analyses into the formation of the embryonic gut, which surprisingly receives contributions from extraembryonic tissue. The fourth and fifth chapters describe my investigation …

    cambridge Repository record for Studying early development using droplet single-cell RNA sequencing (opens in a new tab)