Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Motor neuron disease (MND)"”.
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How can virtual reality benefit the lives of persons with MND?
… in exercise interventions for individuals with motor neuron disease (MND) and other disabilities. We developed Stackly, a space-themed stacking game, as an example of how VR-based exercise programs could be designed for this population. The primary objective of the game is to stack cubes in a …
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Real-time control of a robot using brain activity
Background: Motor neuron disease (MND) describes a range of pathologies in which a person's voluntary muscle control becomes progressively impaired. Whether MND is on-set alone, or - as it commonly would be - paired with muscular atrophy, sufferers of the disease can face difficulty in establishing …
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Phosphoglycerate kinase 1 as a therapeutic target in motor neuron disease
… features in neurodegenerative conditions like motor neuron disease (MND) and supporting cell energy production is an attractive strategy to improve the resilience of neurons to disease pathology. Phosphoglycerate kinase 1 (PGK1) is a key enzyme in the first ATP-producing step in the glycolysis …
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Motor neuron disease in an African population: A review of current literature and a case series of the flail arm variant in the Western Cape
Background: Motor neuron disease (MND) is a devastating neurodegenerative disorder, with recognised phenotypic subtypes. Although prevalent in all parts of the world, little is described in the literature with regards motor neuron disease as it occurs in African populations. Aims: This study had …
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Myasthenia Gravis mimics: An audit of cases identified at Groote Schuur Hospital over 20 years
… 6 functional neurological symptoms (FNS), 6 motor neuron disease (MND) variants, 3 mitochondrial cytopathies, 4 had definite or probable muscular dystrophy (MD), 1 progressive supranuclear palsy and 1 with a multiple sclerosis brainstem relapse. Median age at symptom onset was 10 years for …
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Development and utilization of Luminex biomarker assays for diagnosis and monitoring of neurodegenerative disease
… with protein misfolding include Alzheimer’s disease (AD), Parkinson’s disease (PD), dementia with Lewy bodies (DLB), fronto-temporal lobar degeneration (FTLD), motor neuron disease (MND), Huntington’s disease and the prion diseases. The incidence and prevalence of most of these diseases is …
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Investigating the role of eEF1A2 in motor neuron degeneration
… factor 1A (eEF1A) has been implicated in disease states such as motor neuron degeneration and cancer. Two variants of eEF1A are found in mammals, named eEF1A1 and eEF1A2. These two variants are encoded by different genes, produce proteins which are 92% identical but have very different …
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How is palliative care part of the right to health? The South African evidence
… < 200 cells/mm3 ; and3) patients diagnosed with motor neuron disease (MND). A questionnaire and a validated patient-reported outcome scale, the African Palliative Care Association (APCA) African Palliative Outcome Scale (POS), was administered at first visit. Thereafter participants were followed …