Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Motor network"”.
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Motor Network Organization in Frontal Lobe Epilepsy
… disorder that commonly coincides with functional motor deficits. While the source of these deficits is unknown, it is postulated that repeated seizure activity within the frontal lobe might impact the proximate motor network. To examine this hypothesis, motor networks were compared between …
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From Rest to Action: Functional Connectivity Architecture of the Human Hand Motor Network
Skillful hand motor control relies on complex interactions within a distributed brain network. Over the past two decades, neuroimaging (fMRI) and neurostimulation (TMS) techniques have greatly advanced our understanding of the functional contributions of individual regions. Yet, a central open …
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Reciprocal interactions between feeding and turning motor networks mediate foraging decisions in a predatory sea-slug
… and cooperative interactions between motor networks mediating different behaviors. These decisions are based on appetitive state, i.e., the moment-to-moment integration of sensation, physiological state, and learning. As a generalist predator, the sea-slug Pleurobranchaea californica …
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Motor neuron output in the crustacean cardiac ganglion is organized and maintained by homeostatic conductance relationships
… about the cellular mechanisms in neurons and networks which act to stabilize functional output. Here we utilize large cell motor neurons of the Cancer borealis cardiac ganglion to investigate how these cell's important burst output is generated, maintained and synchronized across cells in a …
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FMRI studies of effects of hearing status on audio-visual speech perception
… cortex (but not primary auditory cortex), speech motor network areas, supramarginal gyrus, thalamus, superior parietal cortex and fusiform gyrus. For hearing impaired subjects, in addition to the areas listed above, Heschl's gyrus, right angular gyrus (AG), cerebellum and regions around right …
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Chemomechanical coupling and motor cycles of the molecular motor myosin V
… structure relies to a large extent on molecular motors. Molecular motors are proteins that are able to convert chemical energy from the hydrolysis of adenosine triphosphate (ATP) into mechanical work. Being about 10 to 100 nanometers in size, the molecules act on a length scale, for which thermal …
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Modeling projection neuron and neuromodulatory effects on a rhythmic neuronal network
… neurons shape the activity of many neural networks. In particular, neuromodulatory substances, which are often released by projection neurons, alter the cellular and/or synaptic properties within a target network. However, neural networks in turn influence projection neuron input via …
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Structural and functional adaptations of the Auditory-Motor System : insights from expertise & disorder
… domains converges on a notion that auditory-motor networks can be remodeled functionally and structurally in response to experiences, studies that seek to evaluate these hypotheses by combining behavioral, functional, and structural measures are rare. Given relatively recent advances in …
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Pitx3Null Mutant (Striatal Dopamine-Deficient) Mice Have Exaggerated Spiny Projection Neuron Responses to l-DOPA and D1 Agonism and Lack Baseline Striatonigral Spiking
… (l-DOPA) strongly stimulates motor activity in parkinsonian patients and animal models of Parkinson's disease. Severe striatal dopamine (DA) loss characterizes Parkinson's disease and its animal models. Given the canonical rate model of Parkinson's Disease pathophysiology based …
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A neuronal switch for approach/avoidance in cost-benefit decision
… avoid appetitive stimuli. A multifunctional turn network is active in response to the unilateral application of the stimulus, promoting the appropriate turn response. The goal of my study was to answer the following questions: 1) How does the nervous system encode the appetitive state of animal? …
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Determining how stable network oscillations arise from neuronal and synaptic mechanisms
… patterns are commonly mediated by neural networks that produce an oscillatory activity pattern, where different neurons maintain a relative phase relationship. This thesis examines the relationships between the cellular and synaptic properties that give rise to stable activity in the form …
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MR Susceptibility Mapping: Improved Quantification and Applications in Developmental Brain Imaging
… nerve impulses. Human cognition, sensation and motor functions all rely on the efficient transmission of neural signals, where compromised myelin integrity may lead to severe neurological and physical disorders. Myelin abnormality can be a hallmark of numerous neurological disorders such as …
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New evidence of functional interactions within the hand motor system
… at first glance simple, ability relies on a network of cerebral areas computing a series of complex neural processes. The core cerebral regions involved in transforming visual inputs into hand actions have been identified within two distinct pareto-frontal networks, the dorsomedial and …