Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Motogenic"”.
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Characterizing the motogenic response of human keratinocytes to epidermal growth factor and transforming growth factor-alpha
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1996.
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Migration Stimulating Factor, the search for inhibitors.
… progression. The MSF protein (70kDa) has potent motogenic activity, with only femtomolar concentrations required to produce half-maximal. The proteolytic degradation of MSF generates the functionally equivalent 43kDa Gel-BD domain and 21kDa IGD peptide. The screening of conditioned medium (CM) …
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Epidermal growth factor and Transforming growth factor α motogenic activities are mediated by Epidermal growth factor receptor : Identification of signalling pathways involved in head and neck cancer
<b> Background</b>: The alteration of Epidermal Growth Factor Receptor (EGFR) plays a major role in the development of Head and Neck cancer. However, the only FDA approved EGFR target for this neoplasm is the drug Cetuximab. Cetuximab can only be used where there is an over-expression of EGFR. …
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The role of scatter factor receptor Met in mobilizing antigen presenting dendritic cells in vivo
… signalling exhibits mitogenic, morphogenic and motogenic activity of various cells e.g. during embryonic development and wound healing. The functional expression of SF receptor/Met in skin DCs has been already shown. In this thesis, a detailed analysis of Met function in two major DC …
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Regulation of Cell Migration by WNK1
… membrane deformation, triggered by a variety of motogenic stimuli, including growth and chemotactic factors, hormones, and elements of the extracellular matrix. My graduate research has focused on the regulation of cell motility by a serine/threonine protein kinase, WNK1 (With No lysine (K)1), so …
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Molecular mechanisms of strain-stimulated intestinal epithelial cell differentiation and migration
… the subsequent downstream strain-induced motogenic response, and suggest that ILK induction by repetitive deformation may contribute to recovery from mucosal injury and restoration of the mucosal barrier in patients with prolonged ileus. ILK may therefore be an important target for …