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Showing 1 to 7 of 7 for “"Motif prediction"”.
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Network motif prediction using generative models for graphs
… between more than two entities. A network motif is one such pattern observed in various realworld networks. Different types of graphs contain different network motifs, an example of which are triangles that often arise in social and biological networks. Motifs model important functional …
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Immunogenetic analysis of HLA Class II in premalignant disease of the cervix and correlation with HPV status
… degradation. The data obtained was used for motif prediction of HPY 16 E6, E7, Ll and L2 sequences that may be capable of binding to these HLA molecules. Motif prediction as well as the binding affinity of predicted peptide motifs for HLA D RB 1 *0401 and DRB 1 *0 10 1 was accomplished using …
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Genome-wide prediction of developmental enhancers and analysis of evolutionary plasticity in Drosophila
… 37 predicted targets of the five above-mentioned motifs have been completed. A positive training set of 15 sequences and a negative training set of 18 sequences have been constructed for embryonic enhancer prediction. Clustering of transcription factor binding sites is the traditional approach for …
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Design and implementation of a cyberinfrastructure for RNA motif search, prediction and analysis
RNA secondary and tertiary structure motifs play important roles in cells. However, very few web servers are available for RNA motif search and prediction. In this dissertation, a cyberinfrastructure, named RNAcyber, capable of performing RNA motif search and prediction, is proposed, designed and …
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Master regulators of neuronal maturation in NGN2 reprogrammed iPSC-derived iNeurons
… of iNeuron maturation were identified using TF motif prediction tools and a dataset combining ATAC-seq and RNA-seq analysis of a granular time-course experiment during NGN2 reprogramming, in the presence and absence of glia. Predicted TFs were found to also be expressed during human cortical …
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Analysis of SMAUG1 protein motifs and interacting partners - linking regulation of phase separation to human disease
… in cells. Using protein domain and short linear motif (SLiMs) deletion mutants, we demonstrated that SMAUG1 phase separation is driven by its structured ‘Smaug similarity region 1’ (SSR1) dimerization domain and a novel intrinsically disordered prion-like domain. In contrast, the RNA-binding …
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Molecular biology of B vitamin metabolism genes and their regulation in Phaeodactylum tricornutum
… methionine synthase (PtMETE). A motif-prediction algorithm revealed a conserved 14 bp motif in the promoters of THIC, METE and other cobalamin-downregulated genes in diatoms that could indicate the co-regulation of cobalamin and thiamine metabolism. Reporter construct experiments …