Global ETD Search
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Showing 1 to 1 of 1 for “"Mosaic chromosomal alterations"”.
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The evolutionary dynamics of clonal haematopoiesis and its progression to acute myeloid leukaemia
… the major forces shaping clonal haematopoiesis. Mosaic chromosomal alterations (mCAs) can also be important drivers in AML and ~3\% of individuals aged ~40-70 have a clonally expanded mCA detectable in >1% of their blood cells. We therefore adapted our framework to quantify the mutation rates and …