Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Morpholino oligonucleotides"”.
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Potential roles for Elf3 in fetal alcohol spectrum disorder and development
… zygotic genome activation. Translation blocking morpholino oligonucleotides were used to implicate Elf3 in epiboly movements during gastrulation and zebrafish tail development. Taken together these results help to strengthen the zebrafish as a model for FASD in addition to giving greater insight …
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The Role of Kitlb on Development of Coordinated Muscular Contractions in the Zebrafish Gastrointestinal Tract
… on the development and maturation of ICC using morpholino oligonucleotides knockdown in zebrafish. Gene expression was quantified using reverse transcriptase PCR analysis. Digital imaging techniques was used to examine morphology of the GI tract. It is anticipated that continued stimulation of …
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Investigating the Impact of Metabolic Dysregulation on Nervous System Development and Function: A Study of CPT2 Deficiency in a Zebrafish Model System
… early vertebrate development. Two knockdown morpholino oligonucleotides (MO), a translation blocker (TB) and a splice blocker (SB), were used to reduce CPT2 expression at the onset of embryonic development and were compared to scrambled, non-specific control (CTRL) MO-injected fish and …
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Characterization of the Placenta-Specific 8.1 Gene Function during Zebrafish Embryogenesis
… of either of two non-overlapping antisense morpholino oligonucleotides: MOs) that effectively reduced Plac8.1 protein levels, embryos displayed an array of defects that phenocopied the class of mutants with defective cilia. Consistently, the motile cilia morphology and motility were impaired …