Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Monozyt"”.
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Role of monocyte subsets in chronic liver injury and liver fibrosis
Monocytes are key players of the innate immune system and crucially modulate tissue inflammation after injury. Mammalian monocytes consist of two principle subsets that display different chemokine receptor expression levels. In humans, the classical monocyte CD14++CD16- subset expresses CCR2, CD64, …
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Monocytes and neutrophils : accomplices in initiation and development of atherosclerosis
Atherosclerosis is currently viewed as a chronic inflammatory disease of the arterial vessel wall with prominent roles for endothelial cells, T lymphocytes and monocyte-derived cells. Hypercholesterolemia is a major risk factor activating these cell types resulting in enhanced expression of cell …
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Untersuchungen zur Modulation der IL-6-Signaltransduktion und zur Funktion der feed back Inhibitoren SOCS1 und SOCS3
To avoid an uncontrolled activation of cells by extracellular stimuli there must exist mechanisms which regulate the signal transduction. Here, regulatory mechanisms of the IL-6 signal transduction pathway were analyzed. In the first part a desensitization of the IL-6 signal could be observed …
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Untersuchung von Zinksignalen während Aktivierung und Reifung in Monozyten
Zinc is an essential trace element for the immune system and regulates the function of monocytes. Intracellular free zinc can bind reversibly to regulatory sites in signaling proteins, whereby changes of free zinc influence signal transduction. To achieve a broad picture about the role of zinc in …