Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Monosodium Urate (MSU) Crystals"”.
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Designing Peptide-Based Biosensors for the Diagnosis of Crystal Arthropathies
… the binding of peptides to the surfaces of monosodium urate (MSU) crystals. MSU crystals accumulate in the joints of patients with acute gout, one of several types of crystal arthropathy. Other arthritides, including pseudo-gout and osteoarthritis, present similar symptoms to gout, but are …
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Cluster Determinant 44 (CD44) Receptor and Gout: Mechanistic Role in Pathogenesis and Therapeutic Targets
… Acute gout is caused by deposition of monosodium urate (MSU) crystals in peripheral joints and surrounding tissues, which activate the resident macrophages to produce pro-inflammatory cytokines and consequently leads to an inflammatory response. The CD44 receptor is highly expressed in …
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Gout Biosensor: Towards the development of a peptide-based diagnostic for crystal arthropathies and Amplifying Graduate Student Perspectives on Supervision and Satisfaction at the University of Calgary
… of gout, there is an increasing need for accurate, cost-effective, and automated diagnostic methods to distinguish between monosodium urate (MSU) crystals, which cause gout, and calcium pyrophosphate dihydrate (CPPD) crystals, responsible for pseudogout. The current gold-standard diagnostic …
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Investigating the Contribution of the Inflammasome to Persistent Pain States
… signals (eg adenosine-5’-triphosphate (ATP), monosodium urate (MSU) crystals).<br/>Data presented in this thesis demonstrates that, following L5 Spinal Nerve Transection (SNT), an animal model of neuropathic pain, inflammasome components NLRP3, ASC, and caspase-1 are upregulated in the injured …