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Showing 1 to 10 of 10 for “"Monolithic column"”.
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Measuring Kinetic Performance of Monolithic and Fused-Core Columns Using Packed-Capillary Liquid-, Ultrahigh-Performance- and Supercritical Fluid Chromatography
… newest LC instruments and the improvements in column technology that resulted in small particle columns and new morphologies like fused-core and monolithic columns imposed the need for methods that enable the selection of chromatographic conditions and columns to achieve the best tradeoff …
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High performance liquid chromatography-tandem mass spectrometry of pharmaceuticals and personal care products in environmental and biological matrices
… chromatography (HPLC) the advantages of new monolithic stationary phases over traditional particle packed beds is becoming apparent. In this work, the performance of a half-metre monolithic column was characterised using van Deemter plots. The separation efficiency of the monolith was …
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Chromatographic Properties of Silica-Based Monolithic HPLC Columns
Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of porous silica. The main advantage of such a network is decreased backpressure due to macropores (2 μM) …
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Development and characterisation of monolithic silica stationary phases for ion chromatography
Silica based monolithic HPLC columns have received much attention in recent years, particularly those modified for reversed-phase separations. However, for ionexchange, silica based monolithic columns have received only limited attention. Therefore, the aim of this work was the development and …
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Preparation, characterisation and modification of porous carbon monolithic materials for chromatographic and electrochemical applications
Chromatographic column technology in HPLC is an ever-growing field. One area in column technology that has captivated attention in recent years is the use of monolithic columns. Monolithic stationary phases for use in liquid chromatography possess unique characteristics, the most significant of …
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Development of a portable microfluidic system for monitoring ions river water
… the possibility of fabricating an anion exchange column through immobilisation with different ion exchangers using a self-fabricated silica monolithic column.A combination of on-chip sample filtration and sample introduction system was investigated using potassium silicate frit and electrophoretic …
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Development of Methods for the Study of Phosphoproteins
… development of a novel strong cation exchange monolithic column for MudPIT (multidimensional protein identification technology) and phosphopeptide isolation. This column, a poly(AMPS-co-PEGDA) monolith containing as high as 40% AMPS, has several favorable features, such as high binding …
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Capillary Electrophoresis of Proteins with Selective On-line Affinity Monoliths
… To accomplish this, an on-line protein G monolithic preconcentrator CE system for enrichment and separation of proteins was developed. This system proved effective for on-line sample extraction, clean-up, preconcentration, and CE of IgG in human serum. IgG from diluted (500 and 65,000 …
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Addressing the Downstream Processing Challenges Within Manufacturing of Oncolytic Rhabdoviruses
… process that was investigated was the use of monolithic column chromatography for Rhabdovirus purification. Two monolithic anion-exchange columns (2 and 6 µm pore size) and one hydrophobic interaction column (6 µm pore size) were used to examine how column pore size affects virus recovery and …
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Desenvolvimento e caracterização de trocador catiônico supermacroporoso para a purificação de macromoléculas
A purificação de biomoléculas, em especial macromoléculas, desperta cada vez mais o interesse de pesquisadores em todo o mundo devido ao potencial de uso das mesmas. Para isso, novas técnicas e materiais vêm sendo desenvolvidos, como os criogéis poliméricos, considerados a nova geração de matrizes …