Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Monocular deprivation"”.
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Acuity, Luminance and Monocular Deprivation in the Cat.
… dominance condition of cortical neurons in monocularly deprived (MD) cats. Monocular deprivation during this period resulted in ocular dominance shifting in favor of the nondeprived eye. They determined that the effects of monocular deprivation were approximately proportional to the period …
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The effects of monocular deprivation on astrocytes in the visual cortex: A stereological study of glial fibrillary acidic protein positive cell bodies and processes
Restriction data tranferred 2014-07-01T11:18:05-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission
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Cellular and molecular analysis of neuronal structure plasticity in the mammalian cortex
… with that seen in response to dark rearing, monocular retinal action potential blockade, or monocular deprivation. Our results show that: (1) cpg15 expression in visual cortex correlates with the electrophysiologically mapped critical period for development of eye-specific preference in the …
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Overexpression of Serum Response Factor in Astrocytes Improves Neuronal Plasticity in a Model of Fetal Alcohol Spectrum Disorders
… (OD) plasticity. For instance, few days of monocular deprivation results in a robust reduction of cortical regions responsive to the deprived eye in normal animals, but not in ferrets exposed early to alcohol. This plasticity deficit can be reversed if alcohol-exposed animals are treated …
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Visual cortical plasticity : the role of parvalbumin expressing inhibitory neurons and abnormalities in models of neurodevelopmental disorders
… ocular dominance (OD) plasticity resulting from monocular deprivation and stimulus-selective response potentiation (SRP) resulting from supplemental visual experience. These two forms of plasticity are triggered by different events but lead to a similar increase in visual cortical response. Both …
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In vivo visualization of CaMKII activity in ocular dominance plasticity
… in single spines before and after 4 hrs of monocular deprivation (MD) in the ferret visual cortex.
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Structural mechanisms of experience-dependent synaptic plasticity in the mouse visual cortex
… (OD) plasticity following brief periods of monocular deprivation (MD) is a classic example of experience-dependent change, which leads to a rapid weakening of cortical responsiveness to the deprived eye and a strengthening of responsiveness to the non-deprived eye. Though there is clear …
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Visualizing inhibitory and excitatory synapse dynamics In vivo
… as shown through their responses following monocular deprivation. We further sought to investigate these events on even shorter time scales by developing a dual color labeling strategy in combination with a newly developed line scanning temporal focusing two photon microscope, enabling …
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Inhibitory synapses are repeatedly assembled and removed at persistent sites in vivo
… by experience-dependent plasticity, we performed monocular deprivation, finding that an ocular dominance shift reduces inhibitory synaptic lifetime and increases recurrence. To investigate the molecular mechanism of rapid inhibitory synapse appearance and removal, I am currently testing molecular …
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Effects of Early Alcohol Exposure on Ocular Dominance Plasticity
… a lack of ODP plasticity after 10 days of monocular deprivation (MD) during the critical period of visual cortex plasticity, as seen by optical imaging of intrinsic signals. This deficit in ODP was rescued by treatment with a phosphodiesterase type 1 inhibitor (PDEi1), vinpocetine. This …
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Critical window in autism : a study on Shank3
… This is most famously supported by the monocular deprivation studies in young kittens, which resulted in irreversible visual impairment in adulthood (Hubel and Wiesel, 1970). However, it is not clear whether this principle extends to more complicated multi-modal behavioral systems. Here …
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Visual System Development in People with One Eye: Behaviour and Structural Neural Correlates
Postnatal monocular deprivation from the surgical removal (enucleation) of one eye in humans results in intact spatial form vision, although its consequences on motion perception development are less clear. Changes in brain structure following early monocular enucleation have either been assessed …
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Requirement for AMPA receptor endocytosis and long-term depression in ocular dominance plasticity
… dominance (OD) shift in visual cortex following monocular deprivation (MD). As in other mammals with binocular vision, MD in mice induces bidirectional plasticity: rapid weakening of responses evoked through the deprived eye is followed by delayed strengthening of open-eye responses. It has been …
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Metabotropic glutamate receptor 5 : a therapeutic target in Fragile X and a regulator of plasticity in visual cortex
… acute and chronic mGluR5 function. In vivo, monocular deprivation results in experience-driven weakening of synaptic strength, which occurs through similar mechanisms as LTD in vitro. We report that this ocular dominance plasticity is impaired following chronic mGluR5 inhibition. This study …
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Non-invasive tuning of experience-dependent plasticity in the primary visual cortex
… of cortical circuits. During the CP, short-term monocular deprivation (MD) induces both functional and anatomical changes in binocular V1, characterized by a weakening of deprived-eye responsiveness via mechanisms of synaptic long-term depression. As the critical period closes, increased …
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Understanding experience-dependent plasticity of cellular and network activity in the mouse primary visual cortex
… dominance (OD) plasticity following temporary monocular deprivation (MD). Here, we used a mouse model of amblyopia and revealed that juvenile OD plasticity, which manifests as depression of response to the deprived eye, requires expression of an immediate early gene, Arc. Also, the juvenile OD …
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Mechanisms of ocular dominance plasticity in the juvenile and adult mouse visual cortex
… development (termed the "critical period"), when monocular deprivation (MD) leads to a rapid weakening of responses evoked through the deprived eye followed by a delayed strengthening of non-deprived eye inputs. It has been proposed that these bidirectional changes occur as a three-stage process: …