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Showing 1 to 7 of 7 for “"Molluscum contagiosum virus"”.
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Characterization of a Mitochondrial Localizing Molluscum Contagiosum Virus Protein: MC163R
<p>Molluscum Contagiosum Virus (MCV) is an obligate human, tumorigenic poxvirus which causes benign skin neoplasms. Reduced inflammation during an MCV infection has been attributed to production of MCV immune evasion molecules (IEMs). IEMs antagonize host immune responses allowing MCV to evade the …
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Characterization of the Anti-Inflammatory Effects of the Molluscum Contagiosum Virus MC160 Protein
Using a series of MC160 deletion mutant proteins, we found that two distinct regions of the MC160 protein independently inhibit TNF-mediated NF-kappaB activation. Specifically, we observed that the second DED of MC160 interacts with procaspase-8 as a means to inhibit NF-kappaB activation, while the …
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Characterization of the anti-inflammatory effects of the Molluscum Contagiosum Virus MC 160 protein
Made available in DSpace on 2017-11-30T21:01:09Z (GMT). No. of bitstreams: 2 7014328.pdf: 6064754 bytes, checksum: 3e9997da641394a81a0d8ace2c57b703 (MD5) license.txt: 4813 bytes, checksum: 715c4321821a960fa1a1e91d2ac7ebce (MD5) Previous issue date: 2008
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Functional Analysis of the Molluscum Contagiosum Virus MC160 Death Effector Domain-Containing Protein RxDL Motif
<p>The <em>Molluscum contagiosum</em> virus (MCV) is a member of the <em>Poxviridae</em> family that causes benign skin lesions. MCV lesions persist on average for 8-12 months in otherwise healthy individuals. MCV lesions are characterized by reduced inflammation. The persistence and reduction of …
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Finding NEMO by the molluscum contagiosum virus MC159 protein and its effect on viral pathogenesis in vivo
Molluscum contagiosum virus (MCV) is a dermatotropic poxvirus that solely infects humans. MCV infections causes benign neoplastic lesions that can persists for few months in children and adults. It is an opportunistic infection in immunocompromised patients. Currently there is no FDA approved drug …
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Characterization of the anti-inflammatory effects of the Molluscum Contagiosum MC159 protein
The Molluscum Contagiosum Virus (MCV) is a dermotropic poxvirus that strictly infects humans. MCV infections produce umbilicated lesions that can persist for six to nine months in children and young adults. Currently there is no cure for MCV infections. Recent evidence suggests that the …