Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Molecular sequence"”.
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THE ROLE OF COMPLEX EVOLUTIONARY DYNAMICS IN MOLECULAR SEQUENCE ANALYSIS
… can be used to quantify selective pressure on molecular sequences. The work contained within this dissertation represents my efforts to create, validate, and test codon models, and to apply them to biologically diverse data sets. Specifically, my objective is to determine the impact and …
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Mollecular Phylogeny of tribolium (Danthoniodeae: Poaceae) and its taxonomic implications
Molecular sequence data from two noncoding regions of D A (ITS AND TRNL-F) Were used to produce a phylogeny for the genus Tribolium and its African and Australasian allies. Topological comparisons of the combined molecular data with the appended existing morphological tree were made. A significant …
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Molecular phylogeny of Tribolium (Danthonioideae: Poaceae) and its taxonomic implications
Molecular sequence data from two noncoding regions of DNA (ITS AND TRNL-F) were used to produce a phylogeny for the genus Tribolium and its African and Australasian allies. Topological comparisons of the combined molecular data with the appended existing morphological tree were made. A significant …
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Algorithms for phylogenetic tree correction in species and cancer evolution
… trees, also known as phylogenies, from molecular sequence data is a fundamental problem in computational biology. Classically, evolutionary trees have been estimated over a set of species, where leaves correspond to extant species and internal nodes correspond to ancestral species. This …
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Phylogeny of the Scarabaeini (Coleptera: Scarabaeidae)
… polarized against 4 members from related tribes. Molecular sequence data from mitochondrial Cytochrome Oxidase subunit I (1197 bp) and 16S ribosomal RNA (461bp) genes of 25 of these taxa were also obtained in an attempt to further resolve broad phylogenetic relationships inferred from …
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A Phylogenetic Analysis of Species Relationships in Hemlocks, the Genus <em>Tsuga</em> (Pinaceae).
… analysis based on structural, biochemical, and molecular sequence data. Characters obtained from published and unpublished literature were combined with new morphological characters from seeds, seedlings, and leaf cuticle material. Results from parsimony analyses of these characters differed …
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A Molecular Phylogenetic Assessment of the North American Lichen Tiger Moths (Lepidoptera; Erebidae; Arctiinae; Lithosiini) with Life History Observations and a Description of a New Species from Central Arizona
… phylogeny of North American lithosiines using molecular sequence data from three genes that have been show to phylogenetically informative in Lepidoptera: cytochrome oxidase subunit I (COI), ribosomal protein S5 (RPS5) and the large subunit 28S ribosomal DNA (28S). Results provide new insights …
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Phylogenetic Study of Apocynaceae Juss. And Aspidosperma Mart. And Zucc
… of this taxonomic group used morphological and molecular characters. The morphological data was similar to that used for PCA, and the molecular sequence data was from both the nuclear genome (ITS-1 and ITS-2) and the chloroplast genome (trnL intron and trnL-F spacer). Phylogenies derived …
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The Lecanicephalidean Fauna of the Stingray Genus Pastinachus (Myliobatiformes: Dasyatidae)
… examined using morphological data augmented by molecular sequence data generated as part of a separate study. Most species identified are likely new to science. Four new species of Flapocephalus and three new species of Anteropora are formally described. Flapocephalus trygonis, the type species, …
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Dynamic Mechanical Properties of Cockroach(Periplaneta americana) Resilin
… to 13 kHz in sound production. Both the protein sequence and composition of natural resilin as well as the dynamic mechanical properties vary substantially across species. This suggests that mechanical properties may be evolutionarily tuned for specific functions within an insect. Here, samples …
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Analysis of essential structural and functional elements in the GTP-regulated signal recognition particle cycle
… using a combination of genetic, biochemical, and molecular sequence analysis techniques. First, I consider the SRP cycle from the perspective of molecular evolution. This analysis provides insight into the significance of structural variation in SRP RNA and identifies novel conserved motifs in the …
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Molecular, Genetic, and Process Approaches for Improving Secreted Pharmaceutical Protein Quality in Komagataella phaffii
… significant quality improvements through molecular sequence engineering of aglycosylated monoclonal antibody backbones. By making informed, conservative mutations to two or three amino acid residues, we greatly reduced product-related variants from proteolysis and N-terminal variations. We …
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Molecular cloning of three genes encoding SNF1/AMPK protein kinases from Drosophila melanogaster.
… in a number of different organisms and recent molecular and biochemical evidence has revealed that the mammalian AMP-activated protein kinases (AMPKs), known to regulate fatty acid and sterol metabolism in response to stress, represent the mammalian homologues of SNF1. Three novel Drosophila …
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A Phylogenetic Study of Cymopterus and Related Genera (Apiaceae)
… ( rps16 intron and trnF-trnL- trnT) DNA sequences were carried out for 129 accessions (22 genera) of North American Apioideae to evaluate the monophyly of Cymopterus , and to ascertain its phylogenetic placement among these other genera. To elucidate evolutionary patterns of fruit and …
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Molecular Phylogenetics and Historical Biogeography of the Tribe Chiococceae (Rubiaceae)
… and biogeography of the Chiococceae using molecular DNA sequence data, and presents novel data on the tribal and generic delimitations, intergeneric relationships, and the origin and dispersal of this group.</p> <p>In the most recent tribal delimitations within subfamily Cinchonoideae, …
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Phylogenetics and biogeography of Australian subterranean Parabathynellidae.
… framework. This thesis provides a comprehensive molecular systematics framework for Australian Parabathynellidae, which is used to explore phylogenetic relationships amongst parabathynellids, their diversity, some aspects of character evolution and their biogeographic history within Australia. In …
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Convergent evolution of betalains in Caryophyllales
… I then discuss convergence at the level of molecular sequence data, and explore ideas of convergence at multiple hierarchies and their integration in the evolution of complex traits. Second, I conduct a reanalysis of the evolution of betalains, using the latest phylogenomic hypothesis of …
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Biogeography and phylogenetics of grassland auchenorrhyncha
… phylogenies of each lineage are required. Using molecular sequence data from multiple genes, I inferred phylogenies for each Auchenorrhyncha lineage with a thorough sampling of each lineage including representatives from all major grasslands of the world. Along with individual phylogenies of each …
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Chemical Footprinting of Polymeric Structure of hnRNPA2 Low Complexity Domain
… or low complexity domains. These low complexity sequences have been shown to induce phase transition in low salt buffer. When incubated at high concentration, certain of these low complexity domains polymerize into labile, amyloid-like fibers. I developed a chemical footprinting method to probe …
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Molecular epidemiology of rabies in Kwazulu-Natal, South Africa
… order to contribute to the understanding of the molecular epidemiology of rabies in the KwaZulu Natal province, and to thereby assist in future surveillance and control efforts, we conducted a molecular sequence analysis of representative panel of viral isolates which were obtained from the …
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