Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Molecular mechanisms of disease"”.
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Genomic analysis of hepatic insulin resistance
… II Diabetes mellitus is a genetically complex disease characterized by insulin resistance in peripheral tissues, which results in simultaneous hyperglycemia and hyperinsulinemia. Because of the prevalence of type II diabetes, many researchers are investigating the genetics of glucose …
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Nuclear Hormone Receptor-Mediated Changes of Cholesterol, Triglyceride, and Bile Acid Physiology in Response to Alterations in Cholesterol Absorption and Bile Acid Pool Size in Mice
The regulation of lipid metabolism is an interwoven series of pathways and events acting in concert to control the nutritional and metabolic needs of the body. When alterations in lipid balance occur they can result in disease, thus an understanding of the pathophysiology, as well as the molecular …
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An investigation of the function of adaptor protein complex 4 (AP-4)
… identities, and thus functional properties, of its membrane-bound organelles. During vesicle trafficking, proteins are selectively sorted into membrane bound transport intermediates by vesicle adaptors, which include those of the highly conserved adaptor protein (AP) complex family. Each AP …