Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"Molecular aspects."”.
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Duchenne muscular dystrophy in South Africa : molecular aspects
… For this reason, it was decided to develop a molecular genetic service for carrier identification and diagnostic predictions. The first step in the South African study involved the collection of biological material from affected individuals. In so doing, minimum prevalence's in the four major …
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MOLECULAR ASPECTS OF DIRECT SOMATIC EMBRYOGENESIS IN ALFALFA (MEDICAGO)
Somatic embryogenesis follows the developmental pattern of the zygote in vitro so it provides a model for early plant development which is more accessible for experimental manipulations. Most of the fundamental research in this area has exploited indirect embryogenic systems which require cells to …
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Molecular aspects of the link between obesity and endometrial cancer.
Five percent of all cancers in postmenopausal women are attributable to being overweight and the incidence rises to 51% in women with endometrial cancer (EC). EC patients that are obese tend to have a poorer outcome, shorter survival rates and more co-morbidities than their non-obese counterparts. …
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Host preference of Perkinsus species: epizootiological, environmental, and molecular aspects
Perkinsus species are protistan parasites of mollusks. In Chesapeake Bay, P. marinus, P. chesapeaki, P. andrewsi, and a Perkinsus isolate from the hard clam Mercenaria mercenaria [Perkinsus sp. (M. mercenaria)] are sympatric. In vitro experiments by others suggest a preference of P. marinus for the …
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Functional and Molecular Aspects of Xenobiotic Transport in Choroid Plexus
… size of the tissue and little is known about the molecular mechanisms, functional complexity and hormonal regulation of organic anion secretion. To further elucidate the underlying mechanisms of organic anion transport across CP epithelium, a primary porcine CP cell culture model was established …
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MOLECULAR ASPECTS OF ENDOTHELIAL CELL FUNCTION AND HYPOXIA-DEPENDENT TUMOR ANGIOGENESIS
… therapy. This thesis aims at investigating molecular aspects of hypoxia-dependent regulation of endothelial cell functions, and to identify new, potential targets of anti-angiogenic therapy. In the first part of the thesis, it is demonstrated that polyamines are potent modulators of …
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Salt stress responses in pear and quince: physiological and molecular aspects
… The aim of the present work was to deepen these aspects and investigate salt stress responses in pear and quince. Two different experiments have been performed: a “short-term” trial in a growth chamber and a “long-term” experiment in the open field. In the short-term experiment, three different …
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Molecular aspects of the link between obesity, insulin resistance and breast cancer.
… cancer is increased in obese individuals. The molecular link between obesity and breast cancer however is not well understood. The study presented here aimed at identifying the molecular mechanisms involved in this link, by testing the hypothesis that high insulin concentration and certain …
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Cellular and Molecular Aspects Of Naïve T cell Priming for Adoptive Immunotherapy
… autologous cells. In this thesis we examine aspects of naïve T cell culture with the aim of improving polyclonal and antigen specific expansions for use in adoptive immunotherapy. We show that while traditional monocyte-derived dendritic cells are variable in phenotype, ex vivo monocytes …
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Molecular Aspects of Nuclear Genome Involvement in S Cytoplasmic Male-Sterile Maize
… or cytoplasmically based mutations. At the molecular level, this thesis project asked if the linear, plasmid-like mitochondrial DNAs (plmtDNAs) S1 and S2, unique to plants carrying cms-S cytoplasms, are involved in the nuclear control phenomenon. Levels of S1 and S2 plmtDNAs were assayed …
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Understanding molecular aspects of mass transport in charged and uncharged dense polymer networks
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Variegate porphyria : molecular aspects of variegate porphyria in South Africa and their biochemical and clinical consequences
… Section 1 of this dissertation examines the molecular basis for VP in South Africa.
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Examining the Behavioral and Molecular Aspects of Adolescent Nicotine Dependence: Implications for Vulnerability to Drugs of Abuse
… period. Our research shows that various aspects of nicotine dependence are both age- and sex-dependent. We observed age- and sex-related differences in both nicotine reward and withdrawal models that imply a heightened vulnerability for adolescents. In addition, we have investigated …
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Hypothalamic orexin neurons and tanycytes: Functional and molecular aspects in a mouse model of temporal lobe epilepsy
This dissertation does not include an abstract.
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Influence of Dietary Protein Intake on the Molecular Aspects of 7,12-Dimethylbenz(a)anthracene Induced Mammary Carcinogenesis (Cancer, Liver)
The influence of prior protein intake in rats on the metabolism and DNA-binding of 7,12-dimethylbenz(a)anthracene (DMBA) by their isolated mammary epithelial cell aggregates was examined. DMBA was metabolized to bay-region anti- and syn- dihydrodiol-epoxides that bound to deoxyadenosine and …
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Suppression of growth factor withdrawal-induced apoptosis in hematopoietic cells: biological consequences and molecular aspects of thrombopoietin stimulation in M07e cells
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Physiological, biochemical and molecular aspects of induced resistance in maize against Bipolaris maydis infection using a zinc-polyphenolic compound and silicon
Maize leaf blight (MLB), caused by the fungus Bipolaris maydis, has great potential to cause considerable losses in the growth and yield of maize. Higher foliar concentration of silicon (Si) or the use of resistance inducers may be promising alternatives for boosting maize resistance against MLB. …
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