Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 77 for “"Molecular approaches"”.
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NUTRITION AND IMMUNITY: MOLECULAR APPROACHES
… this thesis provides both, a phenotypical and molecular characterization of the in vitro impact of these dietary molecules on bovine, porcine and chicken immune responses.
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Microalgae valorization biomass through classical and molecular approaches
… de microalgas mediante aproximaciones clásicas y moleculares, con aplicaciones en Agroalimentación y Biomedicina, así como el desarrollo de aproximaciones de “Proteómica Aplicada” que permitan determinar nuevas aplicaciones biotecnológicas a partir del proteoma de las microalgas. Una de las …
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Molecular approaches to improve soybean plant architecture and seed composition
Soybean is an important agronomic crop which has been widely used as a vegetable oil as well as a source of protein for animals and humans. Among various desired traits for genetic improvement to improve the value of soybean, yield and seed composition deserve attention considering its …
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Using molecular approaches to understand Complex I deficiency in mouse models
… and provide mechanistic insights. However, the molecular bases of genetically-determined complex I dysfunctions remain unclear. Here, two mouse models of complex I-linked mitochondrial disease were analysed structurally by cryo-EM to understand the mechanisms of their pathogenesis. The first …
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Biomechanical and Molecular Approaches to Aortic Valve Disease in a Mouse Model
… progressive alterations in biomechanical and molecular properties of the regional aortic valve are poorly understood. </p><p>Our long-term goal is to leverage the mechanical and mechanistic underpinnings of AVD to develop durable tissue engineered substitutes for use in surgeries. The …
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Molecular Approaches to Facilitate Marker-Assisted Selection for Soybean Aphid Resistance in Soybean
The objective of the fourth study was to test the associated effects of Rag1 on several important agronomic traits including yield in two elite Midwest adapted soybean backgrounds. This study was done because sometimes the introgression of resistance genes from nonadapted sources can carry …
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An investigation of Fusarium verticillioides infection in maize using physiological and molecular approaches
Abstract Maize (Zea mays L.) is an important staple food crop in sub-Saharan Africa providing food security to millions of people. Fusarium verticillioides is an important fungal pathogen that infects maize and causes 'Fusarium Ear Rot' which decreases maize kernel yield and quality. In addition, …
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Bioinformatic and molecular approaches for the analysis of the retinal pigment epithelium (RPE) transcriptome
There is substantial interest in the identification of genes underlying susceptibility to complex human diseases because of the potential utility of such genes in disease prediction and therapy. The complex age-related macular degeneration (AMD) is a prevalent cause of legal blindness in …
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Biochemical and Molecular Approaches to Characterizing the Myrosinase Enzyme System in Horseradish (Armoracia Rusticana)
… with a deduced protein of 538 amino acid and molecular mass of 61.6 kDa. Heterologous expression of ArM1 in Spodoptera frugiperda insect cells resulted in an immune active myrosinase protein product and gave rise to a band of approximately 66 kDa in western blot analysis. ArM1 has the highest …
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USE OF MOLECULAR APPROACHES TO STUDY THE OCCURRENCE OF EXTREMOPHILES AND EXTREMODURES IN NON-EXTREME ENVIRONMENTS
… extreme and non-extreme environments. A range of molecular approaches, in addition to classical microbiology techniques, were used to isolate microorganisms, mainly archaea and bacteria from unusual environments. Halo-bacteria and archaea from non-saline environments and alkaliphilic bacteria and …
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Evaluation and adaptation of molecular approaches for detection and characterization of viruses of the respiratory tract
This study was designed for the development of novel methods for isothermal amplification of nucleic acids using phi29 and Bst DNA polymerases in the detection and characterization of pathogenic viruses of the respiratory tract. High Resolution Melting (HRM) analysis was used in this study for …
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Molecular Approaches to the Genetics of Obesity: Mapping and Characterization of the Murine Diabetes (db) Gene
… is the precise etiology of obesity known at the molecular level. Attempts to identify the molecular basis responsible for obesity in humans have been hampered by difficulties in measuring food intake and energy expenditure to sufficient accuracy, as well as the apparent polygenic control of body …
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Population structure of Atlantic herring, Clupea harengus L., in the northeast Atlantic using phenotypic and molecular approaches
… (meristics, morphometries, otolith shape) and molecular (allozymes, mitochondrial DNA RFLPs, micro satellites) markers were simultaneously used to investigate the morphological and genetic structure of herring populations in the Northeast Atlantic and also to assess the relative usefulness of …
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Functional and molecular approaches to study mu and delta opioid receptor hetero-oligomerization in a model of neuropathic pain
… research aimed to utilize both functional and molecular evidence to identify if a heteromeric mu-delta opioid receptor oligomer (M/DOR) forms in vivo and whether it is upregulated in NP pain. In an animal model of NP pain, animals displayed characteristic behaviours including protecting of the …
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MOLECULAR APPROACHES TO ANALYZE HORIZONTAL RESISTANCE AMONG PLANT SPECIES (MAIZE, SOYBEAN, AND ARABIDOPSIS) TO SYNTENIC FUSARIAL PATHOGENS (F. GRAMINEARUM AND F. VIRGULIFORME)
… by environmental conditions. However, the molecular mechanisms underlying the resistance are still not fully understood. The objectives of this dissertation were to investigate the molecular mechanisms underlying the resistance in different plant species (mainly in maize, soybean, and …
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Molecular approaches to increasing resistance of wheat (Triticum aestivum L.) towards two insect pests; Cereal aphid (Sitobion avenae F.) and Wheat bulb fly (Delia coarctata Fallen).
Cereal aphid (Sitobion avenae) and wheat bulb fly (Delia coarctata) are serious pests of wheat in the UK. At the present, chemical pesticides are used to control these insects, but they are limited in effectiveness, and have undersirable ecological impacts. There is a need to improve wheat …
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Experience, neuroanatomical plasticity and expression of the immediate early gene ZENK in the visual cortex of weanling rats
This investigation combines anatomical and molecular approaches to determine if expression of a specific regulatory transcription factor correlates with morphological plasticity, using a model of experience-dependent plasticity.
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Studies on the Gecko P521 Cone-Type Pigment
In summary, mutational analysis and molecular approaches were used to identify components of the plant disease resistance pathway. The availability of the dnd mutants may facilitate further study of the control of HR cell death, gene-for-gene resistance, and broad spectrum disease resistance in …
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Ecology of nitrogen-fixing bacteria associated with Miscanthus
… bacteria with both culture-based methods and molecular approaches: i. confirming the presence diazotrophs associated with Miscanthus and evaluating their potential to provide nitrogen to the plant; ii. examining how environmental factors may influence the diazotroph communities. In order to …
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