Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Molecular Interaction Networks"”.
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Automatic Reconstruction of the Building Blocks of Molecular Interaction Networks
… highly intricate and difficult to interpret. The molecular interaction networks generated from evaluation of those experiments suggest that cellular functions are carried out by modules of interacting molecules. Reverse-engineering the modular structure of cellular interaction networks has the …
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Comparative analysis of molecular interaction networks : the interplay between spatial and functional organizing principles
The study of biological interaction networks is a central theme in systems biology. Here, we investigate common as well as differentiating principles of molecular interaction networks associated with different levels of molecular organization. They include metabolic pathway maps, protein-protein …
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Biomedical data sharing and analysis at scale : privacy, compaction, and integration
… genomes, single-cell sequencing experiments, and molecular interaction networks. The unprecedented scale, variety, and distributed ownership of emerging biomedical datasets present key computational challenges for sharing and analyzing these data to uncover new scientific insights. This thesis …
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Bridging Methodological Gaps in Network-Based Systems Biology
… cell is controlled by a complex network of interactions among genes, proteins, and other molecules. A major goal of systems biology is to understand and explain the mechanisms by which these interactions govern the cell's response to various conditions. Molecular interaction networks have …
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Systems Biology in an Imperfect World: Modeling Biological Systems with Incomplete Information
… the complex underlying network of biochemical interactions which allow an organism to respond to environmental stimuli. Models of these biological interactions serve as a tool to both codify current understanding of these interactions as well as a starting point for scientific discovery. Due to …