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Showing 1 to 3 of 3 for “"Molecular Docking Simulation"”.

  1. Investigation of the anticancer activity and mechanisms of zinc diethyldithiocarbamate in multiple myeloma

    … were significantly boosted in T lymphocytes. Molecular docking simulation using the AutoDock4 software predicted the potential binding of ZnDDC to the IMiD binding pocket present in CRBN. The study has led to the successful development of a PEGLipo-ZnDDC nano formulation with appreciable …

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  2. Submonomer Synthesis and Structure-activity Relationship Studies of Azapeptide Inhibitors of the Insulin Receptor Tyrosine Kinase

    … of the IRTK to about 80% at 4 mM. Moreover, molecular docking simulation studies indicated that, Ac-DIYET-NH<sub>2</sub>, was bound within the active site of the IRTK with a folded peptide structure that was reminiscent of a turn geometry.</p> <p>In order to identify the location and …

    shu-thes Repository record for Submonomer Synthesis and Structure-activity Relationship Studies of Azapeptide Inhibitors of the Insulin Receptor Tyrosine Kinase (opens in a new tab)

  3. Distinct Functional Phases in Proteins: A Test by Large-Scale Protein Design

    Note: The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access only.

    utswmed Repository record for Distinct Functional Phases in Proteins: A Test by Large-Scale Protein Design (opens in a new tab)