Global ETD Search
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Showing 1 to 3 of 3 for “"Mogrify"”.
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MANIPULATING CELL STATES FOR LEUKAEMIA DIFFERENTIATION THERAPY USING NETWORK PHARMACOLOGY
… study, we demonstrate a novel utility of the MOGRIFY® algorithm in identifying combinations of transcription factors (TFs) and drugs which induce granulocytic differentiation of the NB4 acute promyelocytic leukaemia (APL) cell line. Connectivity Map (CMAP) analysis of these TFs and their …
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A Leap of Fate: Fluid identity, functional modules, and flexible strategies for transcription factor-based reprogramming
… quantitative predictive frameworks (e.g. Mogrify) are now feasible. This offers the opportunity to streamline TF selection and thus reprogramming. Such methods may also open the possibility of new applications, including to target secondary or synthetic cell types or to conduct conversions …