Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Modified cyclodextrins"”.
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Investigations of the solution properties of both unmodified and modified cyclodextrins
… govern the internal motions of the three main, unmodified cyclodextrins (namely a, β and y). The conformational space and dynamics of the interglycosidic dihedral angles, individual glucose tilting and verticallibrations of each glucose unit is investigated. Also the hydrogen bonding across the …
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Design and synthesis of novel β-cyclodextrins and their application as chiral stationary phases for gas chromatography.
… use of systems containing a chiral selector. Cyclodextrins (CDs) and modified cyclodextrins have been used as chiral selectors for their ability to form host-guest complexes with various analytes. The scaffold of the CD allows for assembly of functional groups with controlled geometry. CDs can …
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The design of cyclodextrins for delivery of siRNA - a structure-activity relationship
… This thesis aims to investigate the potential of modified cyclodextrins (CDs) as alternative biomaterials for siRNA delivery and to identify the optimum functional groups to maximise safety and efficacy. To help reduce the overall cationic charge and the potential for in vivo toxicity a …