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Showing 1 to 20 of 4836 for “"Modifications"”.
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Histone Modifications in Trypanosoma Brucei
… organisms, the role of histone posttranslational modifications (PTMs) in influencing transcriptional states has been well-documented. To begin to understand the role of chromatin structure in the regulation of gene expression in trypanosomes, I developed a protocol for the purification of histones …
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Apoptosis-induced chromatin modifications in lupus.
Contains fulltext : 82617.pdf (Publisher’s version ) (Open Access)
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Fluorescent Modifications of Transfer Ribonucleic Acids
Modifications of transfer ribonucleic acids (tRNA's) have been accomplished by chemical and enzymatic methods. The chemical modification has involved the reaction of methylmalondialdehyde (MMDA) with E. coli tRNA('Phe) with the hope of extending the use of substituted malondialdehydes and …
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Grain boundary modifications of manganese ferrite
Complex impedance spectroscopy of Mn ferrite with $\le$1.0 wt% SiO$\sb2$ and CaCO$\sb3$ additions, cooled in air, showed two distinct arcs which were attributed to bulk and grain boundary phenomena. The bulk component was invariant while the grain boundary component varied by less than two orders …
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Compositional modifications in alloys under irradiation
The complex interplay of several physical processes in altering the surface and subsurface compositions of alloys during irradiation has been investigated theoretically using a phenomenological model that includes preferential sputtering, displacement mixing, radiation-enhanced diffusion, …
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Specific Recognition of Atypical Ubiquitin Modifications
… was to better our understanding of atypical Ub modifications with a focus on Ub recognition by linkage-specific binders. In the first part, the UBD family of Npl4-like zinc fingers (NZFs) will be discussed, as this family has previously been shown to be capable of linkage-specific recognition. A …
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AORTIC STIFFNESS MODIFICATIONS AFTER ENDOVASCULAR AORTIC REPAIR
… Objective: This study aimed to evaluate the modifications in aortic stiffness in patients undergoing endovascular aortic repair by measuring pulse wave velocity (PWV) using non-invasive applanation tonometry before and after intervention. Moreover, other parameters measuring cardiac …
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EPIGENETIC MODIFICATIONS REGULATING LIVER HOMEOSTASIS AND TUMORIGENESIS
… studies clearly indicated a role for epigenetic modifications in HCC development. However, it is still unclear whether SWI/SNF mutations have a role in tumor formation. Our data suggest a new role of Arid1A as one of the key players in HCC tumor development. In our study, we show that ARID1A …
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Motor Control Modifications Related to Skill Acquisition
Made available in DSpace on 2014-12-14T16:07:00Z (GMT). No. of bitstreams: 1 8004165.pdf: 7328003 bytes, checksum: 0cbc2768e0af400f74493684b54235e6 (MD5) Previous issue date: 1979
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Endogenous and chemical modifications of model proteins
Protein modifications are ubiquitous in nature, introducing biological complexity and functional diversity. Of the known post-translational modifications, glycosylation is one of the most common and most complex, yet some of the biological implications of this modification remain poorly understood. …
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Synthesis, properties, and modifications of engineering polymers
Amorphous and semi-crystalline poly(arylene ether sulfone) homo- and copolymers and related structures were systematically synthesized via nucleophilic, aromatic substitution reactions using the potassium carbonate/N-methylpyrrolidone synthesis route. In particular, deuterated poly(arylene ether …
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A Study of Modifications to Quantum Mechanics
In this work, the consequences of several modifications to quantum mechanics are examined. These modifications, motivated by string theory, fall into two categories: ones in which the canonical commutation relations between position and momentum are deformed and ones in which the space of states …
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Oscillating Heat Pipe Performance with Evaporator Section Modifications
<p>The continuous development of electronic components to become faster and smaller has led to an increasing problem with thermal management. Thermal management ensures that the component operating temperatures are within a safe range, which maintains performance and improves reliability and …
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Regulation of Histone Covalent Modifications During Yeast Apoptosis
… series of enzyme reactions governing histone modifications that promote a switch from cell proliferation to cell death. Moreover, the conservation of targeted H2B phosphorylation and the enzyme system point to an ancient, late-stage chromatin remodeling event that likely governs cellular …
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In-column polymer modifications: Advancing polymer bonded phases
<p>Glycosylation is the most common post-translational modification affecting protein activities, including delivery to cell surface, binding affinity, and mediating different physiological effects. Separations of glycoproteins and their glycoforms are essential for drug discovery and development, …
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Covalent DNA Modifications in Phage and Bacterial Dynamics
… enzymes and CRISPR systems, and the covalent DNA modifications that neutralize them. Multiple targeted nucleases equip bacteria with an innate immune response against phage, and CRISPR systems provide an adaptive immune response. I report three main studies. 1) To study the human gut microbiome …
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Genetic linkage of multiple modifications in the pig
… heritable modification of target genomes. Modifications can be site-specific or random. Though inefficient, homologous recombination allows for precise genome modification. Random integration can be very efficient, but lacks the opportunity to control the orientation and location of the …
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