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Showing 1 to 20 of 352 for “"Mode of action"”.
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Mode of action of antibiotics
… by a living organism which inhibits the growth of or kills some other living organism. Two of the more important antibiotics that have been studied are penicillin and streptomycin. Although three structural formulae for penicillin have been presented, this antibiotic is generally thought of as a …
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The mode of action of Epicoccum derived antimicrobials
… possess two major limitations: i) emergence of fungal strains that are resistant to their antifungal modes of action, and ii) toxic side effects of the drugs caused by lack of selectivity towards fungal targets. One option to overcome these limitations is thought to be the discovery of …
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The Mode of Action of The Antibiotic Griseofulvin
… in DSpace on 2014-12-09T18:06:24Z (GMT). No. of bitstreams: 1 6604202.pdf: 3351324 bytes, checksum: c827c49bce6885e5f4c6ae0044b42aba (MD5) Previous issue date: 1965
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Studies on the mode of action of the pyrithione biocides
… (NaPT and ZnPT respectively) are inhibitors of both pathogenic fungi and bacteria and are widely used in the cosmetics industry as preservatives. However, little is known of their mode of action. Growth inhibitory data exhibited NaPT to be a poorer growth inhibitor of <i>Escherichia coli</i> …
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The Mode of Action of Certain Chlorinated Hydrocarbons on Insects
… in DSpace on 2014-12-05T21:33:45Z (GMT). No. of bitstreams: 1 0002210.pdf: 3027178 bytes, checksum: adf097dadf5a9bc9ae85bcca4f5b625b (MD5) Previous issue date: 1950
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Investigations into the biosynthesis and mode of action of glycocins
… in DSpace on 2020-10-07T22:48:05Z (GMT). No. of bitstreams: 4 BISWAS-DISSERTATION-2020.pdf: 15779725 bytes, checksum: 517606402c92e43c38a2ea453d5ac34b (MD5) Thesis_Subhanip_full version_Gc_Revised.docx: 30113324 bytes, checksum: 2bb70f923509790902798c8ae362b83b (MD5) LICENSE.txt: 4212 bytes, …
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Novel polyamine based anticancer agents: evaluation of the mode of action.
… prompting this study to evaluate their mode of action. All BNIPPs synthesised exert cytotoxicity in colon, breast and leukaemia cancer cell lines. The most active compound, BNIPSpd exhibits 24-hour IC50 values ranging from 0.47-2.40 mu M in Caco-2 and HT29 colon cancer cells and MCF7 …
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Diallyl polysulfides from garlic: mode of action and applications in agriculture.
Garlic (Allium sativum) contains a wide range of organosulfur compounds which show a variety of biological effects including broad spectrum antibacterial, antifungal and antiviral activity, as well as selective anticancer activity. One highly bioactive class of compounds from garlic are diallyl …
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Deconvoluting drug mode-of-action : transcriptomic evaluation of novel clinical lead antimalarials
… necessitates the discovery and development of effective antimalarials that target both the proliferative asexual parasite stages and the sexual asymptomatic stages that facilitate transmission to a new host. Furthermore, the immense replicative rate and thus mutational capacity of Plasmodium …
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The mode of action of a lipid mobilising factor in cancer cachexia
… by a progressive weight loss due to depletion of both skeletal muscle and adipose tissue. The loss of adipose tissue is due to the production of a tumour-derived lipid mobilising factor (LMF), which has been shown to directly induce lipolysis in isolated epididymal murine white adipocytes. The …
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An Investigation of the Mode of Action of N-Isopropyl Alpha-Chloroacetanilide
… in DSpace on 2014-12-10T17:12:31Z (GMT). No. of bitstreams: 1 6711848.pdf: 4068394 bytes, checksum: 15e61847ada4d3088664e25f70f1a285 (MD5) Previous issue date: 1967
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The anticancer mode of action of the quinone natural product cribrostatin 6
… natural product that induces the death of cancer cell lines in culture, but its mechanism of action and scope of activity are unknown. Quinone based drugs have shown potential in the clinic, making cribrostatin 6 an interesting compound to study. The mode of action of cribrostatin 6 is …
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Design, synthesis and mode of action of short biphenyl and anthranilamide cationic peptidomimetics
… and there is an urgent need for the development of novel antibacterial agents. This research project focused on the development of short cationic peptidomimetics that employ 3'-amino-[1, 1 '-biphenyl)-3-carboxylic acid and anthranilic acid backbones segregated by hydrophobic and cationic groups. …
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Mode of action of organosilicone surfactants in enhancing the performance of Triclopyr herbicide
Triclopyr formulations in the presence or absence of added surfactants were evaluated in relation to optimum control of gorse (Ulex europaeus L.). From a wide range of non-ionic surfactants, superior formulations of triclopyr butoxyethyl ester were selected on the basis of radio labelled uptake and …
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