Global ETD Search
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Showing 1 to 20 of 78 for “"Mobile genetic elements"”.
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Interactions between mobile genetic elements and their bacterial hosts
Integrative and conjugative elements (ICEs) are widespread mobile genetic elements that facilitate the spread of many important genes, including those involved in antibiotic resistance, metabolism, pathogenesis, or symbiosis. These elements are also powerful tools for genetic analyses and …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing endonuclease. The introns are self-splicing ribozymes …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing endonuclease. The introns are self-splicing ribozymes …
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Mobile genetic elements as modulators of the human gut symbiont Bacteroides
Mobile genetic elements (MGEs) facilitate horizontal gene transfer (HGT) in all cellular hosts. In microbial systems, MGEs (e.g. phages, integrative and conjugative elements) are potent drivers of host evolution. Within hosts from the bacterial genus Bacteroides, one of the most common and abundant …
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Investigation of the prevalence and role of mobile genetic elements associated with an aminoglycoside resistance gene, aacC2a, in Acinetobacter baumannii
Includes abstract. Includes bibliographical references (leaves 115-141).
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Characterization of an exclusion mechanism in an integrative and conjugative element in Bacillus subtilis
… gene transfer is the acquisition of new genetic material that can confer novel phenotypes to bacteria and contribute to their evolution. Conjugation is an important mechanism of horizontal gene transfer that involves the direct transfer of DNA between two cells and is mediated by mobile …
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Phenotypic and genotypic characterization of salmonella isolates from chickens and humans in South Sudan.
… antimicrobial susceptibility profiles while the genetic diversity was determined through molecular typing methods that included the detection of virulence genes by PCR and whole genome sequencing of targeted genes. The data was analyzed using SPSS-23 software, for descriptive statistics to obtain …
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Genomics-Based Characterization of the Microbial Community and Plasmidome of the Regina Wastewater Treatment Facility and the Surrounding Aquatic Environment
… how it changes in response to seasonality (2) mobile genetic elements in untreated wastewater and activated sludge, and (3) the antimicrobial resistance (AMR) genes that are released into Wascana creek in the treated wastewater effluent. Samples of WWTP effluent, untreated wastewater, and …
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Specificity and benefits of an exclusion mechanism for a mobile genetic element in Bacillus subtilis
The horizontal transfer of mobile genetic elements, including Integrative and Conjugative Elements (ICEs), plays an essential role in bacterial evolution by helping to promote the spread of genes involved in antibiotic and heavy metal resistance, metabolism, symbiosis, and pathogenicity. Like …
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Integrative Metagenomic Approaches to Study Antibiotic Resistance Genes and Microbial Functions in the Preterm Infant Gut Microbiome
… cohorts and linked ARGs to bacterial hosts and mobile genetic elements. The second study focused on Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus aureus, which commonly colonize the preterm gut and are major causes of neonatal infections. It examined the genomic …
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Conflict between bacteriophages and a mobile genetic element in bacterial immunity
… Many anti-phage defense systems are found within mobile genetic elements, like plasmids, temperate bacteriophages, and integrative and conjugative elements (ICEs). In this thesis, I show how an ICE in the bacterium Bacillus subtilis, called ICEBs1, protects populations of cells from phage …
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Autonomous replication of integrative and conjugative elements
Mobile genetic elements facilitate movement of genes, including those conferring antibiotic resistance and other traits, between bacteria. Integrative and conjugative elements (ICEs), also known as conjugative transposons, are a large family of mobile genetic elements that can transfer between …
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A Study of Antibiotic Resistance Plasmids in Fresh Produce and In Wastewater Environments Using Functional Approaches, Comparative Genomics and Abundance Analysis
… resistance and the mobilome (the community of mobile genetic elements) is responsible for its genetic plasticity. Plasmids are important constituents of the environmental mobilome. The capacity to replicate independently of the bacterial chromosome coupled with the ability to carry clinically …
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Interactions between an integrative and conjugative element and its bacterial host
Conjugative elements are mobile genetic elements that can transfer from a donor bacterium to a recipient via an element-encoded type IV secretion system. Integrative and conjugative elements (ICEs) are an abundant class of conjugative element. ICEs are typically integrated into the bacterial host …
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Regulation of horizontal gene transfer by intercellular peptide signaling in Bacillus subtilis
… have a competitive advantage. Similarly, several mobile genetic elements possess mechanisms that regulate transfer. This regulation maintains stability and promotes dissemination of the element, thereby ensuring its survival. Elucidating the mechanisms that regulate transfer should provide …
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Helper phage capsid size redirection by staphylococcal pathogenicity island SaPI1 involves internal scaffolding proteins.
… virulence factors are encoded on staphylococcal mobile genetic elements. Members of the SaPI family of S. aureus mobile elements encode superantigens and are mobilized at high frequency by specific helper bacteriophages. One remarkable feature of helper phage exploitation by SaPIs is remodeling …
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MODELING REORGANIZATION OF PCF10-INDUCED COMPLEX STRUCTURES IN ENTEROCOCCUS FAECALIS UNDER ERYTHROMYCIN TREATMENT
… can be acquired by this bacterium by way of mobile genetic elements such as plasmids. When E. faecalis with the pCF10 plasmid forms a biofilm it constructs raised complex structures with variable cellular packing above the rigid base. Under treatment by erythromycin, E. faecalis OG1RF(pCF10) …
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Helitrons are enriched in lichenized fungi with long generation length and small distribution sizes
<p>Mobile genetic elements (MGEs) have the potential to drive genome evolution by introducing mutations and causing structural instability and chromosomal rearrangements, particularly under conditions like environmental or genetic stress. In this study, we generated 18 new long-read reference …
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A tripartite survey of CRISPR-Cas diversity: Assessing the contours and limits of natural variation in CRISPR-Cas systems by associated genes and spacer acquisition biases
… homology to anti-phage defence genes and mobile genetic elements even with low CRISPRicity scores, which traditionally been used as the gold standard for proof of co-association with CRISPR-Cas subtypes. A small number of associated antiphage defence genes such as HicAB and DrmB were also …
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A tripartite survey of CRISPR-Cas diversity: Assessing the contours and limits of natural variation in CRISPR-Cas systems by associated genes and spacer acquisition biases
… homology to anti-phage defence genes and mobile genetic elements even with low CRISPRicity scores, which traditionally been used as the gold standard for proof of co-association with CRISPR-Cas subtypes. A small number of associated antiphage defence genes such as HicAB and DrmB were also …
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