Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Mixed effects modeling"”.
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Mixed Effects Modeling and Correlation Structure Selection for High Dimensional Correlated Data
… important but challenging issues in this thesis: mixed-effect modeling with unspecified random effects and correlation structure selection for high-dimensional data. In longitudinal studies, mixed-effects models are important for addressing subject-specific effects. However, most existing …
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Nonlinear mixed effects modeling of gametocyte carriage in patients with uncomplicated malaria
Includes bibliographical references (leaves 96-102)
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The relationship between temperature, rainfall, and tree swallow fledging times
Weather effects such as temperature and precipitation are known to affect reproductive success of many avian species. Weather variables can directly or indirectly influence the fledging success of nestlings. I investigated the effect of minimum temperature, maximum temperature, average temperature, …
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Pharmacokinetic and pharmacodynamic studies of mycophenolic acid in renal transplant recipients
… for conventional study (n=6) and for the PK-PD modeling (n=46), were included.The mean total Cmax and AUC were 11.99B17.22 mg/L and 46.81B121.44 mg.h/L respectively. The free fraction of MPA was ranged from 0.4-1.06%. The mean percent inhibition of IMPDH activity at Cmin and Cmax were …
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Designing Cognitive-Friendly Kitchens: A Mixed-Methods Investigation of Visual Accessibility and Adaptive Technology for Older Adults with Mild Cognitive Impairment
… kitchen with seventeen participants. Linear mixed-effects modeling confirmed that open shelving significantly reduced task duration and physical activity burden and altered visual search patterns, with qualitative data indicating that visual accessibility facilitated cognitive offloading. The …
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Testing A Brief Directive Intervention To Reduce Symptoms Associated With Trauma
… Chung, 2011) of research showing mostly positive effects. The DP included components with research support from studies of expressive writing, prolonged exposure, cognitive processing therapy, and mindfulness-based therapies. Participants were primarily undergraduate students at a large public …
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Evaluating Five Years of Soil Hydrologic Response Following the 2009 Lockheed Fire in the Coastal Santa Cruz Mountains of California
… is insufficient post-fire studies regarding fire-effects on watershed processes such as infiltration and near-surface runoff. Soil infiltration and soil water repellency were evaluated with rainfall simulations, Mini-disk Infiltrometer (MDI) and water drop penetration time tests (WDPT) at sites …
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AUDITORY CUES AND RESPONSE MODES MEDIATE PERIPHERAL VISUAL MISLOCALIZATION
The current study investigates the influence of auditory cues on the localization of briefly presented peripheral visual stimuli. Because the brief presentation of peripheral visual stimuli often leads to mislocalization (Binda, Morrone, & Burr, 2010; Bocianski, Musseler, & Erlhagen, 2008; …
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The real deal: Willingness-to-pay and satiety expectations are greater for real foods versus their images
… have investigated whether 'real food exposure effects' on valuation reflect greater sensitivity to the caloric content of real foods versus images. Here, we compared willingness-to-pay (WTP) for, and expectations about satiety after consuming, everyday snack foods that were displayed as real …
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Predicting Changes in Individual Wellbeing Scores: Mixed Effects Models using Sleep Data from Wearables
… nature of wellbeing assessments, we employ mixed effects modeling techniques where each individual is treated as their own cluster, including Linear Mixed Effects models (LMM) and Mixed Effects Random Forest (MERF), where the latter is benchmarked against classic machine learning models. The …
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The Economic Impact of the Gulf Opportunity Zone Act of 2005
… research questions are tested utilizing linear mixed-effects modeling, multiple ordinary least squares (OLS) regression, and binary logistic regression on a matched sample panel data set using observations from 2002 through 2008. Results indicate that the regional tax policy investment …
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The Effect of Injury Severity on Behavioral Tasks Used for the Assessment of Cognitive Functioning Following Traumatic Brain Injury
… behavioral tasks. Following testing, linear mixed effects modeling was performed assessing performance differences on the four tasks as a function of injury (injured vs. non-injured), injury severity (mild TBI vs. moderate-to-severe TBI), and task interaction. The results indicated that, …
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Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs
… tuberculosis were described using non-linear mixed effects modeling. Pharmacodynamic data was comprised of weekly sputum liquid culture (using mycobacterial growth indicator tubes) time to detection results from 144 patients during the first 2 months of treatment. The effect of drug exposure …
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Response of uneven-aged in interior Douglas-fir stands to precommercial thinning in central interior, British Columbia
… was for height growth, when analyzed using mixed-effects modeling, where no significant differences were found. Trees on the other two spacing regimes also had higher growth in dbh, basal area, and volume than trees on the control plots. The positive growth response to the spacing treatments …
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Making Sense of Educational Change: A longitudinal mixed-methods exploration of how students and teachers come to understand and enact school reform in Brazil
… and *teachers*. I adopt a *longitudinal mixed-methods* approach to this change analysis. Quantitative data include 2,907 responses to a novel survey, administered at the beginning (February) and end (November) of the 2022 academic year across five upper-primary schools. Meanwhile, …
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Using open-source data repository initiatives to investigate impaired white matter connectivity in autism
… to the nested nature of the data, robust linear mixed-effects modeling was used to examine if group differences in diffusion measures were indicated while controlling for several covariates. Compared to NT controls, individuals with ASD showed significantly decreased fractional anisotropy (FA), …
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The Effects of Low Energy Availability and High-Impact Exercise on Bone and Body Composition
… baseline and post-intervention using linear mixed effects modeling. We hypothesized that daily high-impact exercise would have a positive effect on bone by attenuating the rise in bone resorption. In contrast to our hypothesis, bone resorption marker CTX-I increased following both LEA …
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Challenges in the Pharmacokinetics of Therapeutic Proteins
… stages of mice were explored using a nonlinear-mixed effects modeling-based population pharmacokinetic approach.</p> <p>FcRn showed ontogenetic changes in liver, lungs, and kidneys. Two-fold increases in FcRn expression were observed in liver and lungs of 10-day-old mice, whereas FcRn expression …
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Population Pharmacokinetics of Therapeutic Monoclonal Antibodies: Examples and Estimation Method Performance Differences
… of my dissertation research was population PK modeling of therapeutic mAbs, which focused on the population PK modeling of cetuximab, and the evaluation of different estimation methods for population PK modeling of therapeutic mAbs with nonlinear PK characteristics.</p> <p> Cetuximab is a …
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Computer-Administered Patient Reported Outcomes (PRO) and Psychiatric Screening in Outpatient Pain Patients: Effect of a Point-of-Care Biopsychosocial Patient Health Report on Treatment Outcomes
… purpose of the present study was to examine the effects of the regular collection and results feedback prior to the point-of-care on multiple patient-reported outcome (PRO) domains in outpatient pain patients. Maximizing ecological validity and non-disruption of clinic flow were given significant …
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